Potential Biomarkers for Intellectual Disability: A Gipsy Family Study (Articolo in rivista)

Type
Label
  • Potential Biomarkers for Intellectual Disability: A Gipsy Family Study (Articolo in rivista) (literal)
Anno
  • 2014-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.4172/2161-1041.1000138 (literal)
Alternative label
  • Aureli A, Del Beato T, Sebastiani P, Di Rocco M, Marimpietri AE, Graziani A, Sechi E and Di Loreto S. (2014)
    Potential Biomarkers for Intellectual Disability: A Gipsy Family Study
    in Hereditary genetics; OMICS Publishing Group, Los Angeles (Stati Uniti d'America)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Aureli A, Del Beato T, Sebastiani P, Di Rocco M, Marimpietri AE, Graziani A, Sechi E and Di Loreto S. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 3 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 138 (literal)
Note
  • Google Scholar (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Institute of Translational Pharmacology, National Council of Research, L'Aquila, Italy Childhood and Adolescence Neuropsychiatric Clinic, University of L'Aquila, ASL n. 4, L'Aquila, Italy (literal)
Titolo
  • Potential Biomarkers for Intellectual Disability: A Gipsy Family Study (literal)
Abstract
  • Intellectual disability (ID) is frequently due to the synergic action of environmental and genetic factors. Here we describe the particular case of three Gipsy Italian siblings, fifteen, twelve and eleven years old, with ID. Genetic analysis stated that the parents are not consanguineous, and no human leukocyte antigen (HLA) alleles related to autism and/or other neurological disorders are present in the 3 ID patients. Instead, a positive association of ID with brain derived neurotrophic factor (BDNF) (Val66Met and C270T), IL6 (-174) and interleukin 1receptor antagonist (IL1RA) mspa 11100 polymorphisms was demonstrated in these three ID patients. Moreover, serum levels of interleukin 1beta (IL1?), interleukin 6 (IL6) were significantly different between the three patients and controls. (literal)
Editore
Prodotto di
Autore CNR
Insieme di parole chiave

Incoming links:


Autore CNR di
Prodotto
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
Editore di
Insieme di parole chiave di
data.CNR.it