http://www.cnr.it/ontology/cnr/individuo/prodotto/ID298982
Automation and efficiency in the powder structure solution by EXPO package (Abstract/Comunicazione in rivista)
- Type
- Label
- Automation and efficiency in the powder structure solution by EXPO package (Abstract/Comunicazione in rivista) (literal)
- Anno
- 2011-01-01T00:00:00+01:00 (literal)
- Alternative label
A. Altomare, C. Cuocci, C. Giacovazzo, A. Moliterni and R. Rizzi (2011)
Automation and efficiency in the powder structure solution by EXPO package
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- A. Altomare, C. Cuocci, C. Giacovazzo, A. Moliterni and R. Rizzi (literal)
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- Istituto di Cristallografia (IC-CNR) (literal)
- Titolo
- Automation and efficiency in the powder structure solution by EXPO package (literal)
- Abstract
- The EXPO package [1] is a computing program able to successfully
provide the structure solution by starting from minimal information:
the experimental powder diffraction pattern and the chemical formula
of the compound to investigate. EXPO can be used for solving organic,
inorganic, metalorganic structures for a large variety of applications.
Automation and efficiency are suitably combined in EXPO for
performing all the steps of the solution process: indexation, space
group determination, intensity extraction, structure solution, model
optimization, Rietveld refinement.
Automation. Default strategies, identified as the most effective,
are selected for carrying out the solution process automatically and
quickly. They may fail when the experimental data resolution is bad
and/or the structure complexity is remarkable. In these cases, EXPO
can promptly switch to appropriate strategies by profiting by a user
friendly graphical interface.
Efficiency. Innovative theories and computing procedures aiming
at making straightforward all the steps of the solution process are
integrated in EXPO and widely tested. EXPO is continuously updated
and optimized in terms of both computing efficiency and graphical
performances.
In EXPO the two stages based ab initio approach (in the first stage
the intensities are extracted; in the second, the reflections are phased
by Direct Methods) [2] is the automatic choice. The model provided
by Direct Methods is usually partial and approximate because of well
known unavoidable problems in powder diffraction (overlapping,
background, preferred orientation). It can be optimized by default [3],
[4] and/or non-default strategies [5], [6] which are able to reduce the
errors depending on the limited experimental resolution.
A very recent study has regarded a new and more effective figure
of merit [7], alternative to the classical one. It is able to pick up the
phasing trial corresponding to the best solution among several feasible
ones.
Non ab initio method, requesting the knowledge of the expected
molecular geometry and based on Simulated Annealing technique
[8, 9], can optionally be attempted particularly in case of solution of
organic compounds.
Examples of successful automatic runs by EXPO will be discussed
in addition to available special strategies. (literal)
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