T300A Variant of Autophagy ATG16L1 Gene is Associated with Decreased Antigen Sampling and Processing by Dendritic Cells in Pediatric Crohn's Disease (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• T300A Variant of Autophagy ATG16L1 Gene is Associated with Decreased Antigen Sampling and Processing by Dendritic Cells in Pediatric Crohn's Disease (Articolo in rivista) (literal)

Anno

• 2013-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1097/MIB.0b013e3182a6a11c (literal)

Alternative label

• Strisciuglio, Caterina; Miele, Erasmo; Wildenberg, Manon E.; Giugliano, Francesca P.; Andreozzi, Marialuisa; Vitale, Alessandra; Capasso, Francesca; Camarca, Alessandra; Barone, Maria V.; Staiano, Annamaria; Troncone, Riccardo; Gianfrani, Carmela (2013)
  T300A Variant of Autophagy ATG16L1 Gene is Associated with Decreased Antigen Sampling and Processing by Dendritic Cells in Pediatric Crohn's Disease
  in Inflammatory bowel diseases
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Strisciuglio, Caterina; Miele, Erasmo; Wildenberg, Manon E.; Giugliano, Francesca P.; Andreozzi, Marialuisa; Vitale, Alessandra; Capasso, Francesca; Camarca, Alessandra; Barone, Maria V.; Staiano, Annamaria; Troncone, Riccardo; Gianfrani, Carmela (literal)

Pagina inizio

• 2339 (literal)

Pagina fine

• 2348 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 19 (literal)

Rivista

• Inflammatory bowel diseases (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 10 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 11 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• University of Naples Federico II; University of Naples Federico II; University of Amsterdam; University of Amsterdam; University of Amsterdam; Consiglio Nazionale delle Ricerche (CNR) (literal)

Titolo

• T300A Variant of Autophagy ATG16L1 Gene is Associated with Decreased Antigen Sampling and Processing by Dendritic Cells in Pediatric Crohn's Disease (literal)

Abstract

• Background: The single-nucleotide polymorphism T300A of ATG16L1, a Crohn's disease (CD)-associated gene, is responsible for decreased autophagy. This study aimed to investigate the effects of this single-nucleotide polymorphism on the uptake and processing of antigens by dendritic cells (DCs) and the interaction between DC and intestinal epithelium in pediatric patients with CD. (literal)
• Methods: Pediatric patients who homozygously carry either the protective (wild type, n = 7) or risk allele (risk, n = 13) of ATG16L1, as well as heterozygous patients (het, n = 13) were enrolled. The monocyte-derived DC were analyzed for phenotype, antigen sampling, and processing by flow cytometry, whereas the capability of DC to form transepithelial protrusions was determined by confocal microscopy. (literal)

Prodotto di

• Institute of food sciences (ISA) (Istituto)

Autore CNR

• ALESSANDRA CAMARCA (Persona)
• CARMELA GIANFRANI (Unità di personale interno)

Insieme di parole chiave

• Parole chiave di "T300A Variant of Autophagy ATG16L1 Gene is Associated with Decreased Antigen Sampling and Processing by Dendritic Cells in Pediatric Crohn's Disease" (Insieme di parole chiave)

Incoming links:

Prodotto

• Institute of food sciences (ISA) (Istituto)

Autore CNR di

• CARMELA GIANFRANI (Unità di personale interno)
• ALESSANDRA CAMARCA (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Inflammatory bowel diseases (Rivista)

Insieme di parole chiave di

• Parole chiave di "T300A Variant of Autophagy ATG16L1 Gene is Associated with Decreased Antigen Sampling and Processing by Dendritic Cells in Pediatric Crohn's Disease" (Insieme di parole chiave)