Glycosidases and Glycosynthases (Contributo in volume (capitolo o saggio))

Type
Label
  • Glycosidases and Glycosynthases (Contributo in volume (capitolo o saggio)) (literal)
Anno
  • 2014-01-01T00:00:00+01:00 (literal)
Alternative label
  • Beatrice Cobucci-Ponzano and Marco Moracci (2014)
    Glycosidases and Glycosynthases
    Georg Thieme Verlag KG, Stuttgart (Germania) in Biocatalysis in Organic Synthesis, 2014
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Beatrice Cobucci-Ponzano and Marco Moracci (literal)
Pagina inizio
  • 483 (literal)
Pagina fine
  • 506 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#titoloVolume
  • Biocatalysis in Organic Synthesis (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 24 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Consiglio Nazionale delle Ricerche (CNR) (literal)
Titolo
  • Glycosidases and Glycosynthases (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#isbn
  • 978-3-13-174131-8 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autoriVolume
  • Faber K, Fessner W-D , Turner NJ (literal)
Abstract
  • Chemoenzymatic synthesis of glycans as an alternative to classical chemical synthesis has great interest for the exquisite sterospecificity and improved processivity and regioselectivity of the biological catalysts and for the possibility of using reagents less toxic for the environment. Nonetheless, the limitations intrinsic to the natural enzymes promoting sugar synthesis, namely glycoside hydrolases and glycosyltransferases, prompted efforts to engineer the former catalysts obtaining glycosynthases that catalyze the synthesis of oligo-, polysaccharides and glycoconjugates in quantitative yields and from cheap substrates. In this Chapter we show a survey of methods that, exploiting glycosidases and glycosynthases, allow the efficient and reliable preparation of glycans of synthetic relevance. (literal)
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