Phytochemical Composition and Anti-Inflammatory Activity of Extracts from the Whole-Meal Flour of Italian Durum Wheat Cultivars (Articolo in rivista)

Type
Label
  • Phytochemical Composition and Anti-Inflammatory Activity of Extracts from the Whole-Meal Flour of Italian Durum Wheat Cultivars (Articolo in rivista) (literal)
Anno
  • 2015-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.3390/ijms16023512 (literal)
Alternative label
  • Barbara Laddomada, Miriana Durante, Fiorenza Minervini, Antonella Garbetta, Angela Cardinali, Isabella D'Antuono, Sofia Caretto, Antonio Blanco, Giovanni Mita (2015)
    Phytochemical Composition and Anti-Inflammatory Activity of Extracts from the Whole-Meal Flour of Italian Durum Wheat Cultivars
    in International journal of molecular sciences (Online)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Barbara Laddomada, Miriana Durante, Fiorenza Minervini, Antonella Garbetta, Angela Cardinali, Isabella D'Antuono, Sofia Caretto, Antonio Blanco, Giovanni Mita (literal)
Pagina inizio
  • 3512 (literal)
Pagina fine
  • 3527 (literal)
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  • Impact Factor: 2.339 (literal)
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  • 16 (literal)
Rivista
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  • 16 (literal)
Note
  • PubMe (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Istituto di Scienze delle Produzioni Alimentari--CNR, Via Prov.le Monteroni, 73100 Lecce, Italy Istituto di Scienze delle Produzioni Alimentari--CNR, Via Amendola 122/O, 70125 Bari, Italy Dipartimento di Scienze del suolo, della pianta e degli alimenti, Sezione Plant Breeding, Università di Bari, Via Amendola, 165/a, 70124 Bari, Italy (literal)
Titolo
  • Phytochemical Composition and Anti-Inflammatory Activity of Extracts from the Whole-Meal Flour of Italian Durum Wheat Cultivars (literal)
Abstract
  • In this study, the quali-quantitative composition of hydrophilic (phenolic acids) and lipophilic (isoprenoids) extracts from whole-meal flour of five elite Italian durum wheat cultivars was determined. Significant differences in the content of bioactive compounds were observed among the wheat extracts, in particular concerning the content of bound phenolic acids, lutein and ?-tocotrienols. The cultivars Duilio and Svevo showed the highest amount of phenolic acids and isoprenoids, respectively. Extracts were evaluated for their anti-inflammatory activity on HT-29 human colon cells by measuring the levels of interleukin 8 (IL-8) and transforming growth factor ?1 (TGF-?1). Durum wheat extracts significantly inhibited the secretion of the pro-inflammatory IL-8 mediator at 66 ?g/mL of phenolic acids and at 0.2 ?g/mL of isoprenoids. Conversely, the secretion of the anti-inflammatory mediator TGF-?1 was not modified by neither hydrophilic nor lipophilic extracts. These results provide further insight into the potential of durum wheat on human health suggesting the significance of varieties with elevated contents of bioactive components. (literal)
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