3D mapping of microfluidic flow in laboratory-on-a-chip structures using optical tweezers (Articolo in rivista)

Type
Label
  • 3D mapping of microfluidic flow in laboratory-on-a-chip structures using optical tweezers (Articolo in rivista) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Alternative label
  • Mushfique, H; Leach, J; Yin, HB; Di Leonardo, R; Padgett, MJ; Cooper, JM (2008)
    3D mapping of microfluidic flow in laboratory-on-a-chip structures using optical tweezers
    in Analytical chemistry (Wash.)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Mushfique, H; Leach, J; Yin, HB; Di Leonardo, R; Padgett, MJ; Cooper, JM (literal)
Pagina inizio
  • 4237 (literal)
Pagina fine
  • 4240 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 80 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • \"[Mushfique, Hasan; Yin, Huabing; Cooper, Jonathan M.] Univ Glasgow, Dept Elect & Elect Engn, Glasgow G12 8QQ, Lanark, Scotland; [Leach, Jonathan; Padgett, Miles J.] Univ Glasgow, Dept Phys & Astron, SUPA, Glasgow G12 8QQ, Lanark, Scotland; [Di Leonardo, Roberto] Univ Roma La Sapienza, INFM, CRS SOFT, I-00185 Rome, Italy (literal)
Titolo
  • 3D mapping of microfluidic flow in laboratory-on-a-chip structures using optical tweezers (literal)
Abstract
  • Accurate measurement of flow in microfluidic systems is both challenging and important, providing information that can be used to better understand flow fields within laboratory-on-a-chip devices and validate computational simulations. Here, we use optical tweezers within a microfluidic system to measure the velocity vectors of flow fields in two and three dimensions around a microstructures including both molded features within channels and cells. The experimental results are compared to a complex fluid dynamics model showing an agreement between the two of better than 3 mu m/s. This measurement is highly reproducible and minimally invasive, which in the future could be used to provided more in-depth studies of the rheological properties of biological cells and microstructures in laboratory-on-a-chip devices. (literal)
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