http://www.cnr.it/ontology/cnr/individuo/prodotto/ID295083
RNA editing and modifications of RNAs might have favoured the evolution of the triplet genetic code from an ennuplet code (Articolo in rivista)
- Type
- Label
- RNA editing and modifications of RNAs might have favoured the evolution of the triplet genetic code from an ennuplet code (Articolo in rivista) (literal)
- Anno
- 2014-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1016/j.jtbi.2014.05.037 (literal)
- Alternative label
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Di Giulio M.; Moracci M.; Cobucci-Ponzano B. (literal)
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- http://www.scopus.com/inward/record.url?eid=2-s2.0-84904651004&partnerID=q2rCbXpz (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Early Evolution of Life Laboratory, Institute of Biosciences and Bioresources, CNR, Via P. Castellino 111, 80131 Naples, Italy; Glycobiology Laboratory, Institute of Biosciences and Bioresources, CNR, Via P. Castellino 111, 80131 Naples, Italy (literal)
- Titolo
- RNA editing and modifications of RNAs might have favoured the evolution of the triplet genetic code from an ennuplet code (literal)
- Abstract
- Here we suggest that the origin of the genetic code, that is to say, the birth of first mRNAs has been triggered by means of a widespread modification of all RNAs (proto-mRNAs and proto-tRNAs), as today observed in the RNA editing and in post-transcriptional modifications of RNAs, which are considered as fossils of this evolutionary stage of the genetic code origin. We consider also that other mechanisms, such as the trans-translation and ribosome frameshifting, could have favoured the transition from an ennuplet code to a triplet code. Therefore, according to our hypothesis all these mechanisms would be reflexive of this period of the evolutionary history of the genetic code. © 2014. (literal)
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