RNA editing and modifications of RNAs might have favoured the evolution of the triplet genetic code from an ennuplet code (Articolo in rivista)

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Label
  • RNA editing and modifications of RNAs might have favoured the evolution of the triplet genetic code from an ennuplet code (Articolo in rivista) (literal)
Anno
  • 2014-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.jtbi.2014.05.037 (literal)
Alternative label
  • Di Giulio M.; Moracci M.; Cobucci-Ponzano B. (2014)
    RNA editing and modifications of RNAs might have favoured the evolution of the triplet genetic code from an ennuplet code
    in Journal of theoretical biology
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Di Giulio M.; Moracci M.; Cobucci-Ponzano B. (literal)
Pagina inizio
  • 1 (literal)
Pagina fine
  • 5 (literal)
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  • http://www.scopus.com/inward/record.url?eid=2-s2.0-84904651004&partnerID=q2rCbXpz (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 359 (literal)
Rivista
Note
  • Scopu (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Early Evolution of Life Laboratory, Institute of Biosciences and Bioresources, CNR, Via P. Castellino 111, 80131 Naples, Italy; Glycobiology Laboratory, Institute of Biosciences and Bioresources, CNR, Via P. Castellino 111, 80131 Naples, Italy (literal)
Titolo
  • RNA editing and modifications of RNAs might have favoured the evolution of the triplet genetic code from an ennuplet code (literal)
Abstract
  • Here we suggest that the origin of the genetic code, that is to say, the birth of first mRNAs has been triggered by means of a widespread modification of all RNAs (proto-mRNAs and proto-tRNAs), as today observed in the RNA editing and in post-transcriptional modifications of RNAs, which are considered as fossils of this evolutionary stage of the genetic code origin. We consider also that other mechanisms, such as the trans-translation and ribosome frameshifting, could have favoured the transition from an ennuplet code to a triplet code. Therefore, according to our hypothesis all these mechanisms would be reflexive of this period of the evolutionary history of the genetic code. © 2014. (literal)
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