Effect of Bucillamine on Free-Radical-Mediated Degradation of High-Molar-Mass Hyaluronan Induced in vitro by Ascorbic Acid and Cu(II) Ions (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Effect of Bucillamine on Free-Radical-Mediated Degradation of High-Molar-Mass Hyaluronan Induced in vitro by Ascorbic Acid and Cu(II) Ions (Articolo in rivista) (literal)

Anno

• 2014-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.3390/polym6102625 (literal)

Alternative label

• Banasova, Maria; Valachova, Katarina; Rychly, Jozef; Janigova, Ivica; Csomorova, Katarina; Mendichi, Raniero; Mislovicova, Danica; Juranek, Ivo; Soltes, Ladislav (2014)
  Effect of Bucillamine on Free-Radical-Mediated Degradation of High-Molar-Mass Hyaluronan Induced in vitro by Ascorbic Acid and Cu(II) Ions
  in Polymers (Basel)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Banasova, Maria; Valachova, Katarina; Rychly, Jozef; Janigova, Ivica; Csomorova, Katarina; Mendichi, Raniero; Mislovicova, Danica; Juranek, Ivo; Soltes, Ladislav (literal)

Pagina inizio

• 2625 (literal)

Pagina fine

• 2644 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 6 (literal)

Rivista

• Polymers (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 20 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 10 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Slovak Academy of Sciences; Slovak Academy of Sciences; Consiglio Nazionale delle Ricerche (CNR); Slovak Academy of Sciences; Slovak Academy of Sciences (literal)

Titolo

• Effect of Bucillamine on Free-Radical-Mediated Degradation of High-Molar-Mass Hyaluronan Induced in vitro by Ascorbic Acid and Cu(II) Ions (literal)

Abstract

• The bucillamine effect on free-radical-mediated degradation of high-molar-mass hyaluronan (HA) has been elucidated. As HA fragmentation is expected to decrease its dynamic viscosity, rotational viscometry was applied to follow the oxidative HA degradation. Non-isothermal chemiluminometry, thermogravimetry, differential scanning calorimetry, and size-exclusion chromatography (SEC) were applied to characterize resulting HA fragments. Although bucillamine completely inhibited the HA viscosity decrease caused by oxidative system, indicating HA protection from degradation, SEC analysis suggested that some other mechanisms leading to the bucillamine transformations without the decay of the viscosity may come into a play as well. Nonetheless, the link between the reduction of chemiluminescence intensity and disappearance of the differential scanning calorimetry exotherm at 270 degrees C for fragmented HAs indicates a particular role of the bucillamine in preventing the decrease of HA viscosity. (literal)

Prodotto di

• Istituto per lo studio delle macromolecole (ISMAC) (Istituto)
• Catalisi per nuove architetture macromolecolari e sistemi polimerici nanostrutturati e biomimetici (PM.P02.005.003) (Modulo)

Autore CNR

• RANIERO MENDICHI (Unità di personale esterno)

Insieme di parole chiave

• Parole chiave di "Effect of Bucillamine on Free-Radical-Mediated Degradation of High-Molar-Mass Hyaluronan Induced in vitro by Ascorbic Acid and Cu(II) Ions" (Insieme di parole chiave)

Incoming links:

Prodotto

• Istituto per lo studio delle macromolecole (ISMAC) (Istituto)
• Catalisi per nuove architetture macromolecolari e sistemi polimerici nanostrutturati e biomimetici (PM.P02.005.003) (Modulo)

Autore CNR di

• RANIERO MENDICHI (Unità di personale esterno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Polymers (Rivista)

Insieme di parole chiave di

• Parole chiave di "Effect of Bucillamine on Free-Radical-Mediated Degradation of High-Molar-Mass Hyaluronan Induced in vitro by Ascorbic Acid and Cu(II) Ions" (Insieme di parole chiave)