Preparation of core-shell poly(L-lactic) acid-nanocrystalline apatite hollow microspheres for bone repairing applications (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Preparation of core-shell poly(L-lactic) acid-nanocrystalline apatite hollow microspheres for bone repairing applications (Articolo in rivista) (literal)

Anno

• 2012-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1007/s10856-012-4732-1 (literal)

Alternative label

• Iafisco, Michele; Palazzo, Barbara; Ito, Tomoko; Otsuka, Makoto; Senna, Mamoru; Manuel Delgado-Lopez, Jose; Gomez-Morales, Jaime; Tampieri, Anna; Prat, Maria; Rimondini, Lia (2012)
  Preparation of core-shell poly(L-lactic) acid-nanocrystalline apatite hollow microspheres for bone repairing applications
  in Journal of materials science. Materials in medicine
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Iafisco, Michele; Palazzo, Barbara; Ito, Tomoko; Otsuka, Makoto; Senna, Mamoru; Manuel Delgado-Lopez, Jose; Gomez-Morales, Jaime; Tampieri, Anna; Prat, Maria; Rimondini, Lia (literal)

Pagina inizio

• 2659 (literal)

Pagina fine

• 2669 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 23 (literal)

Rivista

• Journal of materials science. Materials in medicine (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 11 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 11 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Alma Mater Studiorum Univ Bologna; University of Eastern Piedmont Amedeo Avogadro; GHIMAS SpA; Musashino Univ; Keio University; IACT CSIC UGR; Consiglio Nazionale delle Ricerche (CNR) (literal)

Titolo

• Preparation of core-shell poly(L-lactic) acid-nanocrystalline apatite hollow microspheres for bone repairing applications (literal)

Abstract

• In this paper, hybrid inorganic-organic core-shell hollow microspheres, made of poly(l-lactic acid) (PLLA) and biomimetic nano apatites (HA), were prepared from biodegradable and biocompatible substances, suitable for bone tissue applications. Preparation is started from Pickering emulsification, i.e., solid particle-stabilized emulsions in the absence of any molecular surfactant, where solid particles adsorbed to an oil-water interface. Stable oil-in-water emulsions were produced using biomimetic 20 nm sized HA nanocrystals as particulate emulsifier and a dichloromethane (CH2Cl2) solution of PLLA as oil phase. Hybrid hollow PLLA microspheres at three different HA nanocrystals surface coverage, ranging from 10 to 50 mu m, were produced. The resulting materials were completely characterized with spectroscopic, calorimetric and microscopic techniques and the cytocompatibility was established by indirect contact tests with both fibroblasts and osteoblasts and direct contact with these latter. They displayed a high level of cytocompatibility and thus represent promising materials for drug delivery systems, cell carriers and scaffolds for regeneration of bone useful in the treatment of orthopaedic, maxillofacial and dental fields. (literal)

Prodotto di

• Processi biomorfici e sviluppo di materiali biomimetici ad elevate performance bio-meccaniche per applicazioni in ingegneria tessutale (ME.P06.018.002) (Modulo)
• Institute of science and technology for ceramics (ISTEC) (Istituto)

Autore CNR

• MICHELE IAFISCO (Unità di personale interno)
• ANNA TAMPIERI (Persona)

Insieme di parole chiave

• Parole chiave di "Preparation of core-shell poly(L-lactic) acid-nanocrystalline apatite hollow microspheres for bone repairing applications" (Insieme di parole chiave)

Incoming links:

Prodotto

• Institute of science and technology for ceramics (ISTEC) (Istituto)
• Processi biomorfici e sviluppo di materiali biomimetici ad elevate performance bio-meccaniche per applicazioni in ingegneria tessutale (ME.P06.018.002) (Modulo)

Autore CNR di

• ANNA TAMPIERI (Persona)
• MICHELE IAFISCO (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of materials science. Materials in medicine (Rivista)

Insieme di parole chiave di

• Parole chiave di "Preparation of core-shell poly(L-lactic) acid-nanocrystalline apatite hollow microspheres for bone repairing applications" (Insieme di parole chiave)