pH-responsive collagen fibrillogenesis in confined droplets induced by vapour diffusion (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• pH-responsive collagen fibrillogenesis in confined droplets induced by vapour diffusion (Articolo in rivista) (literal)

Anno

• 2014-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1007/s10856-014-5189-1 (literal)

Alternative label

• Belen Ramirez-Rodriguez, Gloria; Iafisco, Michele; Tampieri, Anna; Gomez-Morales, Jaime; Manuel Delgado-Lopez, Jose (2014)
  pH-responsive collagen fibrillogenesis in confined droplets induced by vapour diffusion
  in Journal of materials science. Materials in medicine
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Belen Ramirez-Rodriguez, Gloria; Iafisco, Michele; Tampieri, Anna; Gomez-Morales, Jaime; Manuel Delgado-Lopez, Jose (literal)

Pagina inizio

• 2305 (literal)

Pagina fine

• 2312 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 25 (literal)

Rivista

• Journal of materials science. Materials in medicine (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 8 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 10 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Laboratorio de Estudios Cristalograficos, Instituto Andaluz de Ciencias de la Tierra (IACT, CSIC-UGR), Avda. de las Palmeras 4, 18100 Armilla (Granada), Spain; Institute of Science and Technology for Ceramics (ISTEC), National Research Council (CNR), Via Granarolo 64, 48018 Faenza, RA, Italy (literal)

Titolo

• pH-responsive collagen fibrillogenesis in confined droplets induced by vapour diffusion (literal)

Abstract

• A novel methodology for the assembly of collagen fibrils in microliter drops is proposed. It consists in the gradual increase of pH by means of vapour diffusion coming from the decomposition of NH4HCO3 solutions. The pH increase rate as well as the final steady pH of solutions containing collagen can be adjusted by varying the concentration of NH4HCO3. Both parameters are of predominant importance in collagen fibrillogenesis. The effect of these parameters on the kinetic of the fibrillogenesis process and on the fibrils morphology was studied. We found that both the kinetic and the morphology are mainly driven by electrostatic interactions. A gradual increase of pH slows down the formation of collagen fibres and favours the lateral interaction between fibrils producing broader fibres. On the other hand, a rapid increase of pH reduces the lateral electrostatic interactions favouring the formation of thinner fibres. The formation of the D-band periodicity is also a pH-dependent process that occurs after fibrillogenesis when the most stable state of fibres formation has been reached. (literal)

Prodotto di

• Processi di bio-mineralizzazione e sviluppo di compositi bio-ibridi nanostrutturati e funzionalizzati per la medicina rigenerativa (ME.P06.018.001) (Modulo)
• Institute of science and technology for ceramics (ISTEC) (Istituto)

Autore CNR

• ANNA TAMPIERI (Persona)
• MICHELE IAFISCO (Unità di personale interno)

Incoming links:

Prodotto

• Institute of science and technology for ceramics (ISTEC) (Istituto)
• Processi di bio-mineralizzazione e sviluppo di compositi bio-ibridi nanostrutturati e funzionalizzati per la medicina rigenerativa (ME.P06.018.001) (Modulo)

Autore CNR di

• ANNA TAMPIERI (Persona)
• MICHELE IAFISCO (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of materials science. Materials in medicine (Rivista)