Assessment of Multi-Mycotoxin Exposure in Southern Italy by Urinary Multi-Biomarker Determination (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Assessment of Multi-Mycotoxin Exposure in Southern Italy by Urinary Multi-Biomarker Determination (Articolo in rivista) (literal)

Anno

• 2014-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.3390/toxins6020523 (literal)

Alternative label

• Solfrizzo, Michele; Gambacorta, Lucia; Visconti, Angelo (2014)
  Assessment of Multi-Mycotoxin Exposure in Southern Italy by Urinary Multi-Biomarker Determination
  in Toxins (Basel); MDPI AG, Basel (Swaziland)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Solfrizzo, Michele; Gambacorta, Lucia; Visconti, Angelo (literal)

Pagina inizio

• 523 (literal)

Pagina fine

• 538 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.mdpi.com/2072-6651/6/2/523 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 6 (literal)

Rivista

• Toxins (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 16 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 2 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• National Research Council CNR (literal)

Titolo

• Assessment of Multi-Mycotoxin Exposure in Southern Italy by Urinary Multi-Biomarker Determination (literal)

Abstract

• Human exposure assessment to deoxynivalenol (DON), aflatoxin B1 (AFB1), fumonisin B1 (FB1), zearalenone (ZEA) and ochratoxin A (OTA) can be performed by measuring their urinary biomarkers. Suitable biomarkers of exposure for these mycotoxins are DON + de-epoxydeoxynivalenol (DOM-1), aflatoxin M1 (AFM1), FB1, ZEA + alpha-zearalenol (alpha-ZOL) + beta-zearalenol (beta-ZOL) and OTA, respectively. An UPLC-MS/MS multi-biomarker method was used to detect and measure incidence and levels of these biomarkers in urine samples of 52 volunteers resident in Apulia region in Southern Italy. The presence of ZEA + ZOLs, OTA, DON, FB1 and AFM1 were detected in 100%, 100%, 96%, 56% and 6%, of samples, respectively. All samples contained biomarkers of two or more mycotoxins. The mean concentrations of biomarkers ranged from 0.055 ng/mL (FB1) to 11.89 ng/mL (DON). Urinary biomarker concentrations were used to estimate human exposure to multiple mycotoxin. For OTA and DON, 94% and 40% of volunteers, respectively exceeded the tolerable daily intake (TDI) for these mycotoxins. The estimated human exposure to FB1 and ZEA was largely below the TDI for these mycotoxins for all volunteers. (literal)

Editore

• MDPI AG (Editore)

Prodotto di

• Metodi innovativi per l'analisi e la riduzione di micotossine, funghi tossigeni ed allergeni nei prodotti agroalimentari (AG.P05.008.002) (Modulo)
• Istituto di scienze delle produzioni alimentari (ISPA) (Istituto)

Autore CNR

• ANGELO VISCONTI (Unità di personale interno)
• MICHELE SOLFRIZZO (Unità di personale interno)
• LUCIA GAMBACORTA (Persona)

Insieme di parole chiave

• Parole chiave di "Assessment of Multi-Mycotoxin Exposure in Southern Italy by Urinary Multi-Biomarker Determination" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• ANGELO VISCONTI (Unità di personale interno)
• MICHELE SOLFRIZZO (Unità di personale interno)
• LUCIA GAMBACORTA (Persona)

Prodotto

• Istituto di scienze delle produzioni alimentari (ISPA) (Istituto)
• Metodi innovativi per l'analisi e la riduzione di micotossine, funghi tossigeni ed allergeni nei prodotti agroalimentari (AG.P05.008.002) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Toxins (Rivista)

Editore di

• MDPI AG (Editore)

Insieme di parole chiave di

• Parole chiave di "Assessment of Multi-Mycotoxin Exposure in Southern Italy by Urinary Multi-Biomarker Determination" (Insieme di parole chiave)