Genetic variability detected at the lactoferrin locus (LTF) in the Italian Mediterranean river buffalo (Articolo in rivista)

Type
Label
  • Genetic variability detected at the lactoferrin locus (LTF) in the Italian Mediterranean river buffalo (Articolo in rivista) (literal)
Anno
  • 2015-01-01T00:00:00+01:00 (literal)
Alternative label
  • Alfredo Pauciullo, Luigi Ramunno, Niccolà Pietro Paolo Macciotta, Giustino Gaspa, Angelo Coletta, Elisa Apicella, Daniela Gallo, Gianfranco Cosenza (2015)
    Genetic variability detected at the lactoferrin locus (LTF) in the Italian Mediterranean river buffalo
    in Animal production science (Online); Csiro Publishing, Collingwood (Australia)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Alfredo Pauciullo, Luigi Ramunno, Niccolà Pietro Paolo Macciotta, Giustino Gaspa, Angelo Coletta, Elisa Apicella, Daniela Gallo, Gianfranco Cosenza (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url
  • http://www.publish.csiro.au/view/journals/dsp_journals_pip_abstract_Scholar1.cfm?nid=72&pip=AN14612 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • CNR ISPAAM (literal)
Titolo
  • Genetic variability detected at the lactoferrin locus (LTF) in the Italian Mediterranean river buffalo (literal)
Abstract
  • Lactoferrin (LTF) is multi-functional protein belonging to the whey protein fractions of the milk. The gene LTF encoding for such protein is considered a potential candidate for body measurement, milk composition and yield. This study reports on the genetic variability at LTF locus in the Italian Mediterranean river buffalo and its possible association with milk yield. Eleven polymorphic sites were found in the DNA fragment spanning the exons 15-16. In particular, the intron 15 was extremely polymorphic with 9 SNPs detected, whereas the remaining 2 SNPs were exonic mutations (g.88G>A at the exon 15 and g.1351G>A at the exon 16) and both synonymous. The genotyping of the informative samples evidenced 3 haplotypes, whose frequencies were 0.6; 0.3 and 0.1 respectively, whereas the analysis of the exonic SNPs showed a perfect condition of linkage disequilibrium (g.88A/g.1351G and g.88G/g.1351A). The association study carried out by using the SNP g.88G>A showed that buffalo LTF gene has no statistically significant influence on daily milk yield. This study adds knowledge to the genetic variability of a species less investigated than the other ruminant species, that may serve as a useful tool for large-scale screening of buffalo populations. (literal)
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