http://www.cnr.it/ontology/cnr/individuo/prodotto/ID285096

Cephalopods in neuroscience: regulations, research and the 3Rs (Articolo in rivista)

Type

Articolo in rivista (Classe)
Prodotto della ricerca (Classe)

Label

Cephalopods in neuroscience: regulations, research and the 3Rs (Articolo in rivista) (literal)

Anno

2014-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

10.1007/s10158-013-0165-x (literal)

Alternative label

Fiorito, Graziano; Affuso, Andrea; Anderson, David B.; Basil, Jennifer; Bonnaud, Laure; Botta, Giovanni; Cole, Alison; D'Angelo, Livia; De Girolamo, Paolo; Dennison, Ngaire; Dickel, Ludovic; Di Cosmo, Anna; Di Cristo, Carlo; Gestal, Camino; Fonseca, Rute; Grasso, Frank; Kristiansen, Tore; Kuba, Michael; Maffucci, Fulvio; Manciocco, Arianna; Mark, Felix Christopher; Melillo, Daniela; Osorio, Daniel; Palumbo, Anna; Perkins, Kerry; Ponte, Giovanna; Raspa, Marcello; Shashar, Nadav; Smith, Jane; Smith, David; Sykes, Antonio; Villanueva, Roger; Tublitz, Nathan; Zullo, Letizia; Andrews, Paul (2014)
Cephalopods in neuroscience: regulations, research and the 3Rs
in Invertebrate neuroscience
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

Fiorito, Graziano; Affuso, Andrea; Anderson, David B.; Basil, Jennifer; Bonnaud, Laure; Botta, Giovanni; Cole, Alison; D'Angelo, Livia; De Girolamo, Paolo; Dennison, Ngaire; Dickel, Ludovic; Di Cosmo, Anna; Di Cristo, Carlo; Gestal, Camino; Fonseca, Rute; Grasso, Frank; Kristiansen, Tore; Kuba, Michael; Maffucci, Fulvio; Manciocco, Arianna; Mark, Felix Christopher; Melillo, Daniela; Osorio, Daniel; Palumbo, Anna; Perkins, Kerry; Ponte, Giovanna; Raspa, Marcello; Shashar, Nadav; Smith, Jane; Smith, David; Sykes, Antonio; Villanueva, Roger; Tublitz, Nathan; Zullo, Letizia; Andrews, Paul (literal)

Pagina inizio

13 (literal)

Pagina fine

36 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

14 (literal)

Rivista

Invertebrate neuroscience (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

24 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

1 (literal)

Note

ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

Stn Zool Anton Dohrn; ONLUS; BIOGEM SCARL; Pentland Management Syst; Brooklyn College (CUNY); UMR MNHN CNRS 7208 IRD 207 UPMC; PRES University Sorbonne Paris Cite; Minist Salute; BIOGEM SCARL; University of Naples Federico II; Home Off; Univ Caen Basse Normandy; University of Naples Federico II; University of Sannio; Inst Invest Marinas IIM CSIC; University of Copenhagen; Brooklyn College (CUNY); Inst Marine Res; Max Planck Society; Consiglio Nazionale delle Ricerche (CNR); Alfred Wegener Inst Polar & Marine Res; University of Sussex; Consiglio Nazionale delle Ricerche (CNR); Ben Gurion University; Boyd Grp; Federat Lab Anim Sci Assoc FELASA; Universidade do Algarve; Consejo Superior de Investigaciones Cientificas (CSIC); Oregon University System; Istituto Italiano di Tecnologia - IIT; St Georges University London (literal)

Titolo

Cephalopods in neuroscience: regulations, research and the 3Rs (literal)

Abstract

Cephalopods have been utilised in neuroscience research for more than 100 years particularly because of their phenotypic plasticity, complex and centralised nervous system, tractability for studies of learning and cellular mechanisms of memory (e. g. long-term potentiation) and anatomical features facilitating physiological studies (e. g. squid giant axon and synapse). On 1 January 2013, research using any of the about 700 extant species of \"live cephalopods\" became regulated within the European Union by Directive 2010/63/EU on the \"Protection of Animals used for Scientific Purposes\", giving cephalopods the same EU legal protection as previously afforded only to vertebrates. The Directive has a number of implications, particularly for neuroscience research. These include: (1) projects will need justification, authorisation from local competent authorities, and be subject to review including a harm-benefit assessment and adherence to the 3Rs principles (Replacement, Refinement and Reduction). (2) To support project evaluation and compliance with the new EU law, guidelines specific to cephalopods will need to be developed, covering capture, transport, handling, housing, care, maintenance, health monitoring, humane anaesthesia, analgesia and euthanasia. (3) Objective criteria need to be developed to identify signs of pain, suffering, distress and lasting harm particularly in the context of their induction by an experimental procedure. Despite diversity of views existing on some of these topics, this paper reviews the above topics and describes the approaches being taken by the cephalopod research community (represented by the authorship) to produce \"guidelines\" and the potential contribution of neuroscience research to cephalopod welfare. (literal)

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