GENOMIC ORGANIZATION OF THE HUMAN VP16 ACCESSORY PROTEIN, A HOUSEKEEPING GENE (HCFC1) MAPPING TO XQ28 (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• GENOMIC ORGANIZATION OF THE HUMAN VP16 ACCESSORY PROTEIN, A HOUSEKEEPING GENE (HCFC1) MAPPING TO XQ28 (Articolo in rivista) (literal)

Anno

• 1994-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1006/geno.1994.1455 (literal)

Alternative label

• FRATTINI, A; FARANDA, S; REDOLFI, E; ZUCCHI, I; VILLA, A; PATROSSO, MC; STRINA, D; SUSANI, L; VEZZONI, P (1994)
  GENOMIC ORGANIZATION OF THE HUMAN VP16 ACCESSORY PROTEIN, A HOUSEKEEPING GENE (HCFC1) MAPPING TO XQ28
  in Genomics (S. Diego Calif.)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• FRATTINI, A; FARANDA, S; REDOLFI, E; ZUCCHI, I; VILLA, A; PATROSSO, MC; STRINA, D; SUSANI, L; VEZZONI, P (literal)

Pagina inizio

• 30 (literal)

Pagina fine

• 35 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 23 (literal)

Rivista

• Genomics (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 6 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 1 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Istituto di Tecnologie Biomediche Avanzate, Consiglio Nazionale delle Ricerche, Milan, Italy. (literal)

Titolo

• GENOMIC ORGANIZATION OF THE HUMAN VP16 ACCESSORY PROTEIN, A HOUSEKEEPING GENE (HCFC1) MAPPING TO XQ28 (literal)

Abstract

• The region between DXS52 and Factor VIII gene in the human Xq28 chromosomal band contains a G + C-rich isochore to which many genes have been mapped. We report here the isolation and characterization of a transcript mapping about 50 kb telomeric from the vasopressin type 2 receptor gene in a 180-kb YACs/cosmid contig containing the L1CAM gene at its centromeric end. The determined transcribed sequence from a human fetal brain library is identical to that of the recently identified accessory protein HCFC1 (host cell factor, also called C1) that activates herpes simplex virus VP16 (alpha TIF) transactivator protein for association with the octamer motif-binding protein Oct-1 (Cell 74: 115, 1993). The gene is expressed in a ubiquitous pattern and a larger transcript of approximately 10 kb is present in all the tissues tested, while an alternatively spliced RNA of approximately 8.0 kb is present in muscle and heart tissues. Genomic sequencing allowed us to determine that the sequenced transcript is assembled from 26 exons spread over a relatively small genomic region of approximately 24 kb. This allowed us to determine that a previously reported cDNA clone arises from the splicing out of an internal portion of exon 8 which does not change the reading frame. Ah together these results raise the possibility that alternative mRNA processing could partly contribute to the diversity of the polypeptide HCFC1 family in a subset of tissues. (C) 1994 Academic Press, Inc. (literal)

Prodotto di

• Oncologia molecolare : differenziamento cellule epiteliali, caratterizzazione cellule staminali mammarie. (ME.P03.010.001) (Modulo)

Autore CNR

• ANNALISA FRATTINI (Persona)
• ILEANA ZUCCHI (Persona)

Incoming links:

Autore CNR di

• ILEANA ZUCCHI (Persona)
• ANNALISA FRATTINI (Persona)

Prodotto

• Oncologia molecolare : differenziamento cellule epiteliali, caratterizzazione cellule staminali mammarie. (ME.P03.010.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Genomics (Rivista)