Toxic effects induced by mycotoxin fumonisin B1 on equine spermatoza: viability, sperm chromatin structure stability, ROS production and motility (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Toxic effects induced by mycotoxin fumonisin B1 on equine spermatoza: viability, sperm chromatin structure stability, ROS production and motility (Articolo in rivista) (literal)

Anno

• 2010-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.tiv.2010.05.024 (literal)

Alternative label

• Minervini F.; Lacalandra G.M.; Filannino A.; Garbetta A.; Nicassio M.; Dell'Aquila M.E.; Visconti A. (2010)
  Toxic effects induced by mycotoxin fumonisin B1 on equine spermatoza: viability, sperm chromatin structure stability, ROS production and motility
  in In vitro toxicology
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Minervini F.; Lacalandra G.M.; Filannino A.; Garbetta A.; Nicassio M.; Dell'Aquila M.E.; Visconti A. (literal)

Pagina inizio

• 2072 (literal)

Pagina fine

• 2078 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 24 (literal)

Rivista

• In vitro toxicology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 6 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Institute of Sciences of Food Production, CNR, Bari (Italy); Department of Animal Production, University of Bari (italy) (literal)

Titolo

• Toxic effects induced by mycotoxin fumonisin B1 on equine spermatoza: viability, sperm chromatin structure stability, ROS production and motility (literal)

Abstract

• Fumonisin B1 (FB1) is a mycotoxin produced by Fusarium species that exerts its toxic effect through interference with the sphingolipid pathway by inhibiting ceramide synthase. A FB1-dependent sperm toxicity was reported in boars. No information on FB1-related reproductive toxicity in stallions, the most sensitive animal species, has been reported. The aim of the present study was to assess the in vitro toxicity of FB1 on fresh and frozen-thawed equine spermatozoa by analyzing sperm viability, chromatin stability (SCSA) and reactive oxygen species (ROS) production by flow cytometry and sperm motility by CASA system. Fumonisin B1 did not affect viability of fresh spermatozoa after 2 h exposure up to 25 lM. Damage on sperm chromatin structure was observed only in one frozen sample after exposure up to 2.5 ? 10?5 lM FB1 without associated increase of ROS. Increase of ROS, at FB1 levels up to 2.5 ? 10?4 lM, was found on another frozen-thawed sperm sample, may be as a consequence of seminal plasma removal. At 7.5 and 15 lM, FB1 induced reduction of total and progressive motility. (literal)

Prodotto di

• Istituto di scienze delle produzioni alimentari (ISPA) (Istituto)

Autore CNR

• FIORENZA MINERVINI (Unità di personale interno)
• ANGELO VISCONTI (Unità di personale interno)
• Antonella Garbetta (Persona)

Insieme di parole chiave

• Parole chiave di "Toxic effects induced by mycotoxin fumonisin B1 on equine spermatoza: viability, sperm chromatin structure stability, ROS production and motility" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• ANGELO VISCONTI (Unità di personale interno)
• FIORENZA MINERVINI (Unità di personale interno)
• Antonella Garbetta (Persona)

Prodotto

• Istituto di scienze delle produzioni alimentari (ISPA) (Istituto)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• In vitro toxicology (Rivista)

Insieme di parole chiave di

• Parole chiave di "Toxic effects induced by mycotoxin fumonisin B1 on equine spermatoza: viability, sperm chromatin structure stability, ROS production and motility" (Insieme di parole chiave)