GM-CSF Production by Tumor Cells Is Associated with Improved Survival in Colorectal Cancer (Articolo in rivista)

Type
Label
  • GM-CSF Production by Tumor Cells Is Associated with Improved Survival in Colorectal Cancer (Articolo in rivista) (literal)
Anno
  • 2014-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1158/1078-0432.CCR-13-2774 (literal)
Alternative label
  • Nebiker, Christian A.; Han, Junyi; Eppenberger-Castori, Serenella; Iezzi, Giandomenica; Hirt, Christian; Amicarella, Francesca; Cremonesi, Eleonora; Huber, Xaver; Padovan, Elisabetta; Angrisani, Basilio; Droeser, Raoul A.; Rosso, Raffaele; Bolli, Martin; Oertli, Daniel; von Holzen, Urs; Adamina, Michel; Muraro, Manuele G.; Mengus, Chantal; Zajac, Paul; Sconocchia, Giuseppe; Zuber, Markus; Tornillo, Luigi; Terracciano, Luigi; Spagnoli, Giulio C. (2014)
    GM-CSF Production by Tumor Cells Is Associated with Improved Survival in Colorectal Cancer
    in Clinical cancer research (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Nebiker, Christian A.; Han, Junyi; Eppenberger-Castori, Serenella; Iezzi, Giandomenica; Hirt, Christian; Amicarella, Francesca; Cremonesi, Eleonora; Huber, Xaver; Padovan, Elisabetta; Angrisani, Basilio; Droeser, Raoul A.; Rosso, Raffaele; Bolli, Martin; Oertli, Daniel; von Holzen, Urs; Adamina, Michel; Muraro, Manuele G.; Mengus, Chantal; Zajac, Paul; Sconocchia, Giuseppe; Zuber, Markus; Tornillo, Luigi; Terracciano, Luigi; Spagnoli, Giulio C. (literal)
Pagina inizio
  • 3094 (literal)
Pagina fine
  • 3106 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 20 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 13 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 12 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Inst Surg Res; University of Basel; University of Basel; Osped Reg; Osped Reg San Giovanni; Kantonsspital Aarau AG (KSA); Kantonsspital Aarau AG (KSA); Tongji University; Tongji University; Consiglio Nazionale delle Ricerche (CNR) (literal)
Titolo
  • GM-CSF Production by Tumor Cells Is Associated with Improved Survival in Colorectal Cancer (literal)
Abstract
  • Experimental Design: GM-CSF or M-CSF-stimulated peripheral blood CD14(+) cells from healthy donors were cocultured with colorectal cancer cells. Tumor cell proliferation was assessed by H-3-thymidine incorporation. Expression of cytokine genes in colorectal cancer and autologous healthy mucosa was tested by quantitative, real-time PCR. A tumor microarray (TMA) including >1,200 colorectal cancer specimens was stained with GM-CSF- and M-CSF-specific antibodies. Clinicopathological features and overall survival were analyzed. (literal)
  • Purpose: Colorectal cancer infiltration by CD16(+) myeloid cells correlates with improved prognosis. We addressed mechanistic clues and gene and protein expression of cytokines potentially associated with macrophage polarization. (literal)
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