Sequestered Fulvinol-Related Polyacetylenes in Peltodoris atromaculata (Articolo in rivista)

Type
Label
  • Sequestered Fulvinol-Related Polyacetylenes in Peltodoris atromaculata (Articolo in rivista) (literal)
Anno
  • 2014-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1021/np500298h (literal)
Alternative label
  • Ciavatta Maria Letizia, Nuzzo Genoveffa, Takada Kentaro, Mathieu Veronique, Kiss Robert, Villani Guido, Gavagnin Margherita (2014)
    Sequestered Fulvinol-Related Polyacetylenes in Peltodoris atromaculata
    in Journal of natural products (Online)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Ciavatta Maria Letizia, Nuzzo Genoveffa, Takada Kentaro, Mathieu Veronique, Kiss Robert, Villani Guido, Gavagnin Margherita (literal)
Pagina inizio
  • 1678 (literal)
Pagina fine
  • 1684 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 77 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 7 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 7 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Consiglio Nazionale delle Ricerche (CNR), Istituto di Chimica Biomolecolare (ICB), Via Campi Flegrei, 34, 80078 Pozzuoli, Naples, Italy Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkya-ku, 113-8657 Tokyo, Japan Laboratoire de Cance?rologie et de Toxicologie Expe?rimentale, Faculte?de Pharmacie, Universite?Libre de Bruxelles (ULB), Campus de la Plaine, Boulevard du Triomphe, 1050, Brussels, Belgium (literal)
Titolo
  • Sequestered Fulvinol-Related Polyacetylenes in Peltodoris atromaculata (literal)
Abstract
  • The Mediterranean dorid nudibranch Peltodoris atromaculata that had been collected while feeding on Haliclona fulva was shown to sequester long-chain fulvinol-like polyacetylene metabolites (compounds 2-5) from the prey. They were isolated along with previously reported bromorenierins from the diethyl ether extracts of both the mollusk and the sponge. Their structures were elucidated by NMR spectroscopy and tandem FABMS analysis. Compound 5 exhibited in vitro growth inhibitory effects against the SKMEL-28 melanoma cell line. (literal)
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