http://www.cnr.it/ontology/cnr/individuo/prodotto/ID282025
Live cell cytoplasm staining and selective labeling of intracellular proteins by non-toxic cell-permeant thiophene fluorophores (Articolo in rivista)
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- Label
- Live cell cytoplasm staining and selective labeling of intracellular proteins by non-toxic cell-permeant thiophene fluorophores (Articolo in rivista) (literal)
- Anno
- 2014-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1039/c3ob41982g (literal)
- Alternative label
Di Maria F.[ 1,2 ] ; Palama I.E.[ 3 ] ; Baroncini M.[ 4 ] ; Barbieri A.[ 2 ]; Bongini A.[ 4 ]; Bizzarri R.[ 5 ]; Gigli G.[ 4,6 ]; Barbarella G.[ 2,7 ] (2014)
Live cell cytoplasm staining and selective labeling of intracellular proteins by non-toxic cell-permeant thiophene fluorophores
in Organic & biomolecular chemistry
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Di Maria F.[ 1,2 ] ; Palama I.E.[ 3 ] ; Baroncini M.[ 4 ] ; Barbieri A.[ 2 ]; Bongini A.[ 4 ]; Bizzarri R.[ 5 ]; Gigli G.[ 4,6 ]; Barbarella G.[ 2,7 ] (literal)
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- Note
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- [ 1 ] CNR, Lab MIST ER, I-40129 Bologna, Italy
[ 2 ] CNR, Inst Organ Synth & Photoreact, I-40129 Bologna, Italy
[ 3 ] Univ Salento, NNL CNR Nanosci Inst, I-73100 Lecce, Italy
[ 4 ] Univ Bologna, Dip Chim G Ciamician, I-40126 Bologna, Italy
[ 5 ] CNR, Ist Biofis, I-56124 Pisa, Italy
[ 6 ] Univ Salento, Dip Ingn Innovaz, I-73100 Lecce, Italy
[ 7 ] CNR, Mediteknol Srl, I-40129 Bologna, Italy (literal)
- Titolo
- Live cell cytoplasm staining and selective labeling of intracellular proteins by non-toxic cell-permeant thiophene fluorophores (literal)
- Abstract
- A structurally correlated series of cell-permeant thiophene fluorophores, characterized by intense green or red fluorescence inside live mouse embryonic fibroblasts, was developed. The fluorophores displayed rapid internalization, excellent retention inside the cells, and high optical stability in the cytosolic environment and did not alter cell viability and reproducibility. Depending on the molecular structure, they experienced distinct fate inside the cells: from bright and lasting staining of the cytoplasm to selective tagging of a small set of globular proteins. This journal is © The Royal Society of Chemistry 2014. (literal)
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