Extracellular circulating viral microRNAs: Current knowledge and perspectives (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Extracellular circulating viral microRNAs: Current knowledge and perspectives (Articolo in rivista) (literal)

Anno

• 2013-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.3389/fgene.2013.00120 (literal)

Alternative label

• Alessandro Laganà, Francesco Russo, Dario Veneziano, Sebastiano Di Bella, Rosalba Giugno, Alfredo Pulvirenti, Carlo M. Croce, Alfredo Ferro (2013)
  Extracellular circulating viral microRNAs: Current knowledge and perspectives
  in Frontiers in genetics
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Alessandro Laganà, Francesco Russo, Dario Veneziano, Sebastiano Di Bella, Rosalba Giugno, Alfredo Pulvirenti, Carlo M. Croce, Alfredo Ferro (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.scopus.com/inward/record.url?eid=2-s2.0-84883496491&partnerID=q2rCbXpz (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 4 (literal)

Rivista

• Frontiers in genetics (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• JUN (literal)

Note

• Scopu (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Laboratory for Integrative System Medicine, Institute of Informatics and Telematics and Institute of Clinical Physiology, National Research Council, Pisa, Italy; Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH, United States; Department of Clinical and Molecular Biomedicine, University of Catania, Catania, Italy (literal)

Titolo

• Extracellular circulating viral microRNAs: Current knowledge and perspectives (literal)

Abstract

• MicroRNAs (miRNAs) are small non-coding RNAs responsible of post-transcriptional regulation of gene expression through interaction with messenger RNAs (mRNAs). They are involved in important biological processes and are often dysregulated in a variety of diseases, including cancer and infections. Viruses also encode their own sets of miRNAs, which they use to control the expression of either the host's genes and/or their own. In the past few years evidence of the presence of cellular miRNAs in extracellular human body fluids such as serum, plasma, saliva, and urine has accumulated. They have been found either cofractionate with the Argonaute2 protein or in membrane-bound vesicles such as exosomes. Although little is known about the role of circulating miRNAs, it has been demonstrated that miRNAs secreted by virus-infected cells are transferred to and act in uninfected recipient cells. In this work we summarize the current knowledge on viral circulating miRNAs and provide a few examples of computational prediction of their function. © 2013 Laganà, Russo, Veneziano, Di Bella, Giugno, Pulvirenti, Croce and Ferro. (literal)

Prodotto di

• Algoritmica per bioinformatica (INT.P02.003.003) (Modulo)
• Institute for informatics and telematics (IIT) (Istituto)

Insieme di parole chiave

• Keywords of "Extracellular circulating viral microRNAs: Current knowledge and perspectives" (Insieme di parole chiave)

Incoming links:

Prodotto

• Institute for informatics and telematics (IIT) (Istituto)
• Algoritmica per bioinformatica (INT.P02.003.003) (Modulo)

Autore CNR di

• http://www.cnr.it/ontology/cnr/individuo/unitaDiPersonaleEsterno/ID23003

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Frontiers in genetics (Rivista)

Insieme di parole chiave di

• Keywords of "Extracellular circulating viral microRNAs: Current knowledge and perspectives" (Insieme di parole chiave)