Testis transcriptome analysis in male infertility: new insight on the pathogenesis of oligo-azoospermia in cases with and without AZFc microdeletion. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Testis transcriptome analysis in male infertility: new insight on the pathogenesis of oligo-azoospermia in cases with and without AZFc microdeletion. (Articolo in rivista) (literal)

Anno

• 2010-01-01T00:00:00+01:00 (literal)

Alternative label

• Gatta V, Raicu F, Ferlin A, Antonucci I, Scioletti AP, Garolla A, Palka G, Foresta C, Stuppia L. (2010)
  Testis transcriptome analysis in male infertility: new insight on the pathogenesis of oligo-azoospermia in cases with and without AZFc microdeletion.
  in BMC genomics
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Gatta V, Raicu F, Ferlin A, Antonucci I, Scioletti AP, Garolla A, Palka G, Foresta C, Stuppia L. (literal)

Pagina inizio

• 401 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 11 (literal)

Rivista

• BMC genomics (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Department of Biomedical Sciences, \"G. d'Annunzio\" University, Chieti- Pescara, Italy, Aging Center Research, \"G. d'Annunzio\" Foundation, Chieti- Pescara, Italy, Carol Davila University of Medicine and Pharmacy, Genetics Chair, Bucharest, Romania, Department of Clinical Sciences and Imaging, \"G. d'Annunzio\" University, Chieti-Pescara, Italy, Centre for Male Gamete Cryopreservation, Department of Histology, Microbiology, and Medical Biotechnologies, University of Padova, Italy, Human Genetics Division, \"Spirito Santo\" Hospital, Pescara, Italy IGM-CNR c/o IOR, Bologna, Italy (literal)

Titolo

• Testis transcriptome analysis in male infertility: new insight on the pathogenesis of oligo-azoospermia in cases with and without AZFc microdeletion. (literal)

Abstract

• BACKGROUND: About 10% of cases of male infertility are due to the presence of microdeletions within the long arm of the Y chromosome (Yq). Despite the large literature covering this critical issue, very little is known about the pathogenic mechanism leading to spermatogenesis disruption in patients carrying these microdeletions. In order to identify the presence of specific molecular pathways leading to spermatogenic damage, testicular gene expression profiling was carried out by employing a microarray assay in 16 patients carrying an AZFc microdeletion or affected by idiopathic infertility. Hierarchical clustering was performed pooling the data set from 26 experiments (16 patients, 10 replicates). (literal)

Prodotto di

• Institute of molecular genetics (IGM) (Istituto)
• Bersagli molecolari per il controllo della progressione tumorale (ME.P03.012.001) (Modulo)

Autore CNR

• LIBORIO STUPPIA (Unità di personale esterno)

Incoming links:

Prodotto

• Institute of molecular genetics (IGM) (Istituto)
• Bersagli molecolari per il controllo della progressione tumorale (ME.P03.012.001) (Modulo)

Autore CNR di

• LIBORIO STUPPIA (Unità di personale esterno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• BMC genomics (Rivista)