http://www.cnr.it/ontology/cnr/individuo/prodotto/ID27661
Distribution of centromeric proteins and PARP-1 during mitosis and apoptosis. (Articolo in rivista)
- Type
- Label
- Distribution of centromeric proteins and PARP-1 during mitosis and apoptosis. (Articolo in rivista) (literal)
- Anno
- 2009-01-01T00:00:00+01:00 (literal)
- Alternative label
Perdoni F, Bottone MG, Soldani C, Veneroni P, Alpini C, Pellicciari C, Scovassi AI. (2009)
Distribution of centromeric proteins and PARP-1 during mitosis and apoptosis.
in Annals of the New York Academy of Sciences
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Perdoni F, Bottone MG, Soldani C, Veneroni P, Alpini C, Pellicciari C, Scovassi AI. (literal)
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- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- IGM, Università di Pavia (literal)
- Titolo
- Distribution of centromeric proteins and PARP-1 during mitosis and apoptosis. (literal)
- Abstract
- A large complex of proteins, called CENPs, are associated with centromeric DNA. Some of them exhibit a cell cycle-related expression (e.g., CENP-E and -F) and are required for the transition from interphase to mitosis, whereas constitutive proteins (e.g., CENP-A, -B, -C, -G, and -H) reside permanently at the centromere and are essential for the correct kinetochore assembly. Poly(ADP-ribose) polymerase-1 (PARP-1), which plays an active role in many basic processes, was described as a possible regulator of CENPs. By multicolor immunofluorescence we therefore analyzed the distribution of PARP-1 and its interaction with CENP-B, -E, and -F during mitosis and apoptosis. (literal)
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