Ultrasonic and Electromagnetic Enhancement of a Culture of Human SAOS-2 Osteoblasts Seeded onto a Titanium Plasma-Spray Surface. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Ultrasonic and Electromagnetic Enhancement of a Culture of Human SAOS-2 Osteoblasts Seeded onto a Titanium Plasma-Spray Surface. (Articolo in rivista) (literal)

Anno

• 2009-01-01T00:00:00+01:00 (literal)

Alternative label

• Fassina L, Saino E, Sbarra MS, Visai L, De Angelis MG, Mazzini G, Benazzo F, Magenes G. (2009)
  Ultrasonic and Electromagnetic Enhancement of a Culture of Human SAOS-2 Osteoblasts Seeded onto a Titanium Plasma-Spray Surface.
  in Tissue engineering
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Fassina L, Saino E, Sbarra MS, Visai L, De Angelis MG, Mazzini G, Benazzo F, Magenes G. (literal)

Pagina inizio

• 233 (literal)

Pagina fine

• 242 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 15 (literal)

Rivista

• Tissue engineering (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Dipartimento di Informatica e Sistemistica, Universita' Pavia, Italy; Centro di Ingegneria Tissutale (C.I.T.), Universita' di Pavia, Italy; Dipartimento di Biochimica, Università di Pavia, Italy; Dipartimento di Medicina Sperimentale, Universita' di Pavia, Italy; IGM-CNR Istochimica e Citometria, Dipartimento di Biologia Animale, Universita' di Pavia, Italy; Dipartimento SMEC, IRCCS San Matteo, Universita' di Pavia , Pavia, Italy . (literal)

Titolo

• Ultrasonic and Electromagnetic Enhancement of a Culture of Human SAOS-2 Osteoblasts Seeded onto a Titanium Plasma-Spray Surface. (literal)

Abstract

• Several studies suggest that the surface coating of titanium could play an important role in bone tissue engineering. In the present study, we have followed a particular biomimetic strategy where ultrasonically or electromagnetically stimulated SAOS-2 human osteoblasts proliferated and built their extracellular matrix on a titanium plasma-spray surface. In comparison with control conditions, the ultrasonic stimulation (average power, 149 mW; frequency, 1.5 MHz) and the electromagnetic stimulation (magnetic field intensity, 2 mT; frequency, 75 Hz) caused higher cell proliferation, and increased surface coating with decorin, osteocalcin, osteopontin, and type I collagen together with higher incorporation of calcium and phosphorus inside the extracellular matrix. The immunofluorescence related to the preceding bone matrix proteins showed their colocalization in the cell-rich areas. The use of the two physical stimulations aimed at obtaining the coating of the rough titanium plasma-spray surface in terms of cell colonization and deposition of extracellular matrix. The superficially cultured biomaterial could be theoretically used, in clinical applications, as an implant for bone repair. (literal)

Prodotto di

• Sviluppi metodologici in citometria e applicazioni alla sperimentazione biomedica; in vitro imaging (ME.P06.010.001) (Modulo)
• Institute of molecular genetics (IGM) (Istituto)

Autore CNR

• GIULIANO MAZZINI (Persona)

Incoming links:

Prodotto

• Institute of molecular genetics (IGM) (Istituto)
• Sviluppi metodologici in citometria e applicazioni alla sperimentazione biomedica; in vitro imaging (ME.P06.010.001) (Modulo)

Autore CNR di

• GIULIANO MAZZINI (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Tissue engineering (Rivista)