Perichromatin fibrils as early markers of transcriptional alterations. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Perichromatin fibrils as early markers of transcriptional alterations. (Articolo in rivista) (literal)

Anno

• 2008-01-01T00:00:00+01:00 (literal)

Alternative label

• Biggiogera M, Cisterna B, Spedito A, Vecchio L, Malatesta M. (2008)
  Perichromatin fibrils as early markers of transcriptional alterations.
  in Differentiation (Lond.)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Biggiogera M, Cisterna B, Spedito A, Vecchio L, Malatesta M. (literal)

Pagina inizio

• 57 (literal)

Pagina fine

• 65 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 76 (literal)

Rivista

• Differentiation (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• DOI: 10.1111/j.1432-0436.2007.00211. (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto

• articolo su rivista (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• (BM; CB; SA; VL)Dipartimento di Biologia Animale, Laboratorio di Biologia Cellulare e Neurobiologia, University of Pavia, and (BM) Istochemistry and Cytometry section, Institute of Molecular Genetics, Consiglio Nazionale delle Ricerche, 27100 Pavia,Italy; (MM) Dipartimento di Scienze Morfologiche Biomediche, Sezione di Anatomia e Istologia, University of Verona, Verona, Italy. (literal)

Titolo

• Perichromatin fibrils as early markers of transcriptional alterations. (literal)

Abstract

• Perichromatin fibrils represent the morphological expression of transcription and co-transcriptional processing of pre-mRNA. They can be considered, hence, an example of work in progress. High resolution techniques such as electron microscopy demonstrate that perichromatin fibrils play a role as early markers of transcriptional alterations. In this paper, we review some experimental and physiological conditions impairing or modulating transcription as well as their effects on perichromatin fibrils. In all the situations reported, perichromatin fibrils show modifications in their amount and/or their associated proteins. Their movements are also affected, as well as their export or their intra-nuclear storage forms. Perichromatin fibrils therefore represent highly sensitive markers not only for monitoring transcriptional and processing rate but also for identifying the maturation level of pre-mRNA/mRNA occurring in the cell nucleus and the functional correlation with the cellular metabolic state. (literal)

Prodotto di

• Sviluppi metodologici in citometria e applicazioni alla sperimentazione biomedica; in vitro imaging (ME.P06.010.001) (Modulo)
• Institute of molecular genetics (IGM) (Istituto)

Autore CNR

• Marco Biggiogera (Unità di personale esterno)

Insieme di parole chiave

• Keywords of "Perichromatin fibrils as early markers of transcriptional alterations." (Insieme di parole chiave)

Incoming links:

Prodotto

• Institute of molecular genetics (IGM) (Istituto)
• Sviluppi metodologici in citometria e applicazioni alla sperimentazione biomedica; in vitro imaging (ME.P06.010.001) (Modulo)

Autore CNR di

• Marco Biggiogera (Unità di personale esterno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Differentiation (Rivista)

Insieme di parole chiave di

• Keywords of "Perichromatin fibrils as early markers of transcriptional alterations." (Insieme di parole chiave)