Quercetin: a pleiotropic kinase inhibitor against cancer (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Quercetin: a pleiotropic kinase inhibitor against cancer (Articolo in rivista) (literal)

Anno

• 2014-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1007/978-3-642-38007-5_11 (literal)

Alternative label

• Russo, Gian Luigi; Russo, Maria; Spagnuolo, Carmela; Tedesco, Idolo; Bilotto, Stefania; Iannitti, Roberta; Palumbo, Rosanna (2014)
  Quercetin: a pleiotropic kinase inhibitor against cancer
  in Cancer treatment and research
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Russo, Gian Luigi; Russo, Maria; Spagnuolo, Carmela; Tedesco, Idolo; Bilotto, Stefania; Iannitti, Roberta; Palumbo, Rosanna (literal)

Pagina inizio

• 185 (literal)

Pagina fine

• 205 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 159 (literal)

Rivista

• Cancer treatment and research (Rivista)

Note

• PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Istituto Scienze dell'Alimentazione, Istituto di Biostrutture e Bioimmagini - Consiglio Nazionale delle Ricerche (literal)

Titolo

• Quercetin: a pleiotropic kinase inhibitor against cancer (literal)

Abstract

• Increased consumption of fruits and vegetables can represent an easy strategy to significantly reduce the incidence of cancer. From this observation, derived mostly from epidemiological data, the new field of chemoprevention has emerged in the primary and secondary prevention of cancer. Chemoprevention is defined as the use of natural or synthetic compounds able to stop, reverse, or delay the process of tumorigenesis in its early stages. A large number of phytochemicals are potentially capable of simultaneously inhibiting and modulating several key factors regulating cell proliferation in cancer cells. Quercetin is a flavonoid possessing potential chemopreventive properties. It is a functionally pleiotropic molecule, possessing multiple intracellular targets, affecting different cell signaling processes usually altered in cancer cells, with limited toxicity on normal cells. Simultaneously targeting multiple pathways may help to kill malignant cells and slow down the onset of drug resistance. Among the different substrates triggered by quercetin, we have reviewed the ability of the molecule to inhibit protein kinases involved in deregulated cell growth in cancer cells. (literal)

Prodotto di

• Institute of food sciences (ISA) (Istituto)
• Institute of biostructure and bioimaging (IBB) (Istituto)
• Alimenti e salute dell'uomo (AG.P05.005.001) (Modulo)

Autore CNR

• GIAN LUIGI RUSSO (Persona)
• MARIA RUSSO (Persona)
• IDOLO TEDESCO (Unità di personale interno)
• ROSANNA PALUMBO (Unità di personale interno)

Insieme di parole chiave

• Keywords of "Quercetin: a pleiotropic kinase inhibitor against cancer" (Insieme di parole chiave)

Incoming links:

Prodotto

• Institute of food sciences (ISA) (Istituto)
• Institute of biostructure and bioimaging (IBB) (Istituto)
• Alimenti e salute dell'uomo (AG.P05.005.001) (Modulo)

Autore CNR di

• GIAN LUIGI RUSSO (Persona)
• ROSANNA PALUMBO (Unità di personale interno)
• MARIA RUSSO (Persona)
• IDOLO TEDESCO (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Cancer treatment and research (Rivista)

Insieme di parole chiave di

• Keywords of "Quercetin: a pleiotropic kinase inhibitor against cancer" (Insieme di parole chiave)