http://www.cnr.it/ontology/cnr/individuo/prodotto/ID273880

Zn2+/Cd2+ optical discrimination by fluorescent chemosensors based on 8-hydroxyquinoline derivatives and sulfur-containing macrocyclic units (Articolo in rivista)

Type

Prodotto della ricerca (Classe)
Articolo in rivista (Classe)

Label

Zn2+/Cd2+ optical discrimination by fluorescent chemosensors based on 8-hydroxyquinoline derivatives and sulfur-containing macrocyclic units (Articolo in rivista) (literal)

Anno

2013-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

10.1039/c3dt51292d (literal)

Alternative label

Aragoni MC, Arca M, Bencini A, Caltagirone C, Garau A, Isaia F, Light ME, Lippolis V, Lodeiro C, Mameli M, Montis R, Mostallino MC, Pintus A, Puccioni S (2013)
Zn2+/Cd2+ optical discrimination by fluorescent chemosensors based on 8-hydroxyquinoline derivatives and sulfur-containing macrocyclic units
in Dalton transactions (2003. Print)
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

Aragoni MC, Arca M, Bencini A, Caltagirone C, Garau A, Isaia F, Light ME, Lippolis V, Lodeiro C, Mameli M, Montis R, Mostallino MC, Pintus A, Puccioni S (literal)

Pagina inizio

14516 (literal)

Pagina fine

14530 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

http://pubs.rsc.org (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

42 (literal)

Rivista

Dalton transactions (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

15 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

40 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

Istituto di Neuroscienze (CNR) Cagliari; Dipartimento di Scienze Chimiche e Geologiche, Università degli Studi di Cagliari, Cagliari; Dipartimento di Chimica Ugo Schiff, Università di Firenze, Firenze; BIOSCOPE Group, Department of Chemistry, CQFB-REQUIMTE, Faculty of Science and Technology, University NOVA of Lisbon, Lisbon; School of Chemistry, University of Southampton, Highfield, Southampton (literal)

Titolo

Zn2+/Cd2+ optical discrimination by fluorescent chemosensors based on 8-hydroxyquinoline derivatives and sulfur-containing macrocyclic units (literal)

Abstract

Four new fluorescent chemosensors for metal ions based on 8-hydroxyquinoline (8-HDQ) derivatives and sulfur-containing macrocyclic units were synthesized and characterized, namely 1-(5-chloro-8-hydroxy-7-quinolinylmethyl)-1-aza-4,7,10-trithiacyclododecane (L1), 1-(5-chloro-8-hydroxy-7-quinolinylmethyl)-1-aza-4,13-dithia-7,10-dioxacyclopentadecane (L2), 1-(8-hydroxy-2-quinolinylmethyl)-1-aza-4,7,10-trithiacyclododecane (L3), and 1-(8-hydroxy-2-quinolinylmethyl)-1-aza-4,13-dithia-7,10-dioxacyclopentadecane (L4). Preliminary fluorimetric titrations indicated L1 as the only member of the family of ligands to give a selective CHEF-type response to the presence of Zn(2+) in MeCN-H2O (1:1, v/v) solutions, which allowed imaging of this metal ion in Cos-7 cells in vitro. The other ligands either did not show any fluorescence response (L3, L4) to any of the metal ions considered (Cu(2+), Zn(2+), Cd(2+), Hg(2+) and Pb(2+)) or gave (L2) a CHEF-type response also to the presence of Cd(2+). The coordination properties of L1 towards Zn(2+) were, therefore, fully investigated by potentiometric measurements and absorption and emission spectroscopy at different pH values, which indicated that the formation of 2:1 L1/Zn(2+) complexes is responsible for the CHEF-type effect observed. The complexes [Zn(L1)2H2O](BF4)2 and [Zn(L3)](ClO4)2 were characterized in the solid state by X-ray crystallography, and DFT calculations were performed to understand the origin of the Zn(2+)/Cd(2+) optical discrimination of the 8-HDQ-based \"conjugate\" fluorescent chemosensors reported. (literal)

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