Modeling the contrasting Neolithic male lineage expansions in Europe and Africa (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Modeling the contrasting Neolithic male lineage expansions in Europe and Africa (Articolo in rivista) (literal)

Anno

• 2013-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1186/2041-2223-4-25 (literal)

Alternative label

• Sikora MJ, Colonna V, Xue Y, Tyler-Smith C. (2013)
  Modeling the contrasting Neolithic male lineage expansions in Europe and Africa
  in Investigative genetics
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Sikora MJ, Colonna V, Xue Y, Tyler-Smith C. (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 4 (literal)

Rivista

• Investigative genetics (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 1 (literal)

Note

• PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK Institute of Genetics and Biophysics, National Research Council (CNR), 80125 Naples, Italy (literal)

Titolo

• Modeling the contrasting Neolithic male lineage expansions in Europe and Africa (literal)

Abstract

• Patterns of genetic variation in a population carry information about the prehistory of the population, and for the human Y chromosome an especially informative phylogenetic tree has previously been constructed from fully-sequenced chromosomes. This revealed contrasting bifurcating and starlike phylogenies for the major lineages associated with the Neolithic expansions in sub-Saharan Africa and Western Europe, respectively. RESULTS: We used coalescent simulations to investigate the range of demographic models most likely to produce the phylogenetic structures observed in Africa and Europe, assessing the starting and ending genetic effective population sizes, duration of the expansion, and time when expansion ended. The best-fitting models in Africa and Europe are very different. In Africa, the expansion took about 12 thousand years, ending very recently; it started from approximately 40 men and numbers expanded approximately 50-fold. In Europe, the expansion was much more rapid, taking only a few generations and occurring as soon as the major R1b lineage entered Europe; it started from just one to three men, whose numbers expanded more than a thousandfold. CONCLUSIONS: Although highly simplified, the demographic model we have used captures key elements of the differences between the male Neolithic expansions in Africa and Europe, and is consistent with archaeological findings. (literal)

Prodotto di

• Institute of genetics and biophysics \"Adriano Buzzati Traverso\" (IGB) (Istituto)
• Approccio multidisciplinare per la definizione di networks molecolari regolanti tratti ad eredità mendeliana e multifattoriale (SV.P18.005.001) (Modulo)

Autore CNR

• VINCENZA COLONNA (Persona)

Incoming links:

Prodotto

• Institute of genetics and biophysics \"Adriano Buzzati Traverso\" (IGB) (Istituto)
• Approccio multidisciplinare per la definizione di networks molecolari regolanti tratti ad eredità mendeliana e multifattoriale (SV.P18.005.001) (Modulo)

Autore CNR di

• VINCENZA COLONNA (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Investigative genetics (Rivista)