In vitro cellular detoxification of triethylene glycol dimethacrylate by adduct formation with N-acetylcysteine (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• In vitro cellular detoxification of triethylene glycol dimethacrylate by adduct formation with N-acetylcysteine (Articolo in rivista) (literal)

Anno

• 2013-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.dental.2013.04.023 (literal)

Alternative label

• Spagnuolo, Gianrico; Desiderio, Claudia; Rivieccio, Virginia; Amato, Massimo; Rossetti, Diana Valeria; D'Anto, Vincenzo; Schweikl, Helmut; Lupi, Alessandro; Rengo, Sandro; Nocca, Giuseppina (2013)
  In vitro cellular detoxification of triethylene glycol dimethacrylate by adduct formation with N-acetylcysteine
  in Dental materials
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Spagnuolo, Gianrico; Desiderio, Claudia; Rivieccio, Virginia; Amato, Massimo; Rossetti, Diana Valeria; D'Anto, Vincenzo; Schweikl, Helmut; Lupi, Alessandro; Rengo, Sandro; Nocca, Giuseppina (literal)

Pagina inizio

• E153 (literal)

Pagina fine

• E160 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 29 (literal)

Rivista

• Dental materials (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 8 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 8 (literal)

Note

• ISI Web of Science (WoS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• University of Naples Federico II; Consiglio Nazionale delle Ricerche (CNR); University of Salerno; Catholic University of the Sacred Heart; Bambino Gesu Childrens Hospital; University of Regensburg (literal)

Titolo

• In vitro cellular detoxification of triethylene glycol dimethacrylate by adduct formation with N-acetylcysteine (literal)

Abstract

• Objective. Various protective effects of N-acetylcysteine (NAC) against triethylene glycol dimethacrylate (TEGDMA)-induced cell damage have been demonstrated, but so far there is no evidence on NAC direct monomer detoxification mechanism. Here, we hypothesized that NAC might reduce TEGDMA cytotoxicity due to direct NAC adduct formation. (literal)
• Methods. We measured the cytotoxic effects of TEGDMA in presence and in absence of NAC by MTT test. Then we analyzed the presence of TEGDMA-NAC adduct formation in extracellular and intracellular compartments by capillary electrophoresis-UV detection (CE-UV) and capillary electrophoresis-mass spectrometry (CE-MS) analytical techniques. Moreover, we quantified the effective intracellular and extracellular TEGDMA concentrations through HPLC in the presence and absence of 10 mmol/L NAC. (literal)

Prodotto di

• Istituto di chimica del riconoscimento molecolare (ICRM) (Istituto)
• Proteomica salivare (PM.P06.008.002) (Modulo)

Autore CNR

• CLAUDIA DESIDERIO (Unità di personale interno)

Insieme di parole chiave

• Parole chiave di "In vitro cellular detoxification of triethylene glycol dimethacrylate by adduct formation with N-acetylcysteine" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• CLAUDIA DESIDERIO (Unità di personale interno)
• http://www.cnr.it/ontology/cnr/individuo/unitaDiPersonaleEsterno/ID22553

Prodotto

• Istituto di chimica del riconoscimento molecolare (ICRM) (Istituto)
• Proteomica salivare (PM.P06.008.002) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Dental materials (Rivista)

Insieme di parole chiave di

• Parole chiave di "In vitro cellular detoxification of triethylene glycol dimethacrylate by adduct formation with N-acetylcysteine" (Insieme di parole chiave)