Engineering new metabolic capabilities in bacteria: lessons from recombinant cellulolytic strategies (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Engineering new metabolic capabilities in bacteria: lessons from recombinant cellulolytic strategies (Articolo in rivista) (literal)

Anno

• 2012-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.tibtech.2011.08.003 (literal)

Alternative label

• Mazzoli R., Lamberti C., Pessione E. (2012)
  Engineering new metabolic capabilities in bacteria: lessons from recombinant cellulolytic strategies
  in Trends in biotechnology (Regul. ed.)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Mazzoli R., Lamberti C., Pessione E. (literal)

Pagina inizio

• 111 (literal)

Pagina fine

• 119 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 30 (literal)

Rivista

• Trends in biotechnology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Univ Turin, Dipartimento Biol Anim & Uomo, I-10123 Turin, Italy (literal)

Titolo

• Engineering new metabolic capabilities in bacteria: lessons from recombinant cellulolytic strategies (literal)

Abstract

• Cellulose waste biomass is the most attractive substrate for 'biorefinery strategies' producing high-value products (e.g. fuels or plastics) by fermentation. However, traditional biomass bioconversions are economically inefficient multistep processes. Thus far, no microorganisms able to perform single-step fermentation into products (consolidated bioprocessing; CBP) have been isolated. Metabolic engineering is currently employed to develop recombinant microorganisms suitable for CBP. The heterologous expression of extracellular proteins (e.g. cellulases or hemicellulases) is the key feature of recombinant cellulolytic strategies, conferring cellulolytic ability to microorganisms exhibiting high product yields and titers. Although more molecular tools are becoming available, efficient heterologous expression of secreted proteins is still a challenge. The present review summarizes both bottlenecks and solutions of organism engineering for biomass biorefinery strategies. (literal)

Prodotto di

• Qualità delle filiere alimentari tipiche del Nord Italia mediante piattaforme tecnologiche integrate (AG.P05.012.001) (Modulo)
• Istituto di scienze delle produzioni alimentari (ISPA) (Istituto)

Autore CNR

• CRISTINA LAMBERTI (Persona)

Incoming links:

Prodotto

• Istituto di scienze delle produzioni alimentari (ISPA) (Istituto)
• Qualità delle filiere alimentari tipiche del Nord Italia mediante piattaforme tecnologiche integrate (AG.P05.012.001) (Modulo)

Autore CNR di

• CRISTINA LAMBERTI (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Trends in biotechnology (Rivista)