Evolutionary conservation of otd/Otx2 transcription factor action: a genome-wide microarray analysis in Drosophila. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Evolutionary conservation of otd/Otx2 transcription factor action: a genome-wide microarray analysis in Drosophila. (Articolo in rivista) (literal)

Anno

• 2002-01-01T00:00:00+01:00 (literal)

Alternative label

• Montalta-He H, Leemans R, Loop T, Strahm M, Certa U, Primig M, Acampora D, Simeone A, Reichert H. (2002)
  Evolutionary conservation of otd/Otx2 transcription factor action: a genome-wide microarray analysis in Drosophila.
  in Genome biology (Online)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Montalta-He H, Leemans R, Loop T, Strahm M, Certa U, Primig M, Acampora D, Simeone A, Reichert H. (literal)

Pagina inizio

• 15.1 (literal)

Pagina fine

• 15.15 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 3 (literal)

Rivista

• Genome biology (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Univ Basel, Inst Zool, Biozentrum, Pharmazentrum, CH-4056 Basel, Switzerland F Hoffmann La Roche Ltd, Roche Genet Pharmaceut Div, CH-4070 Basel, Switzerland F Hoffmann La Roche Ltd, Roche Bioinformat, CH-4070 Basel, Switzerland Kings Coll London, MRC Ctr Dev Neurobiol, London SE1 1UL, England (literal)

Titolo

• Evolutionary conservation of otd/Otx2 transcription factor action: a genome-wide microarray analysis in Drosophila. (literal)

Abstract

• Background: Homeobox genes of the orthodenticle (otd)/Otx family have conserved roles in the embryogenesis of head and brain. Gene replacement experiments show that the Drosophila otd gene and orthologous mammalian Otx genes are functionally equivalent, in that overexpression of either gene in null mutants of Drosophila or mouse can restore defects in cephalic and brain development. This suggests that otd and Otx genes control a comparable subset of downstream target genes in either organism. Here we use quantitative transcript imaging to analyze this equivalence of otd and Otx gene action at a genomic level. (literal)

Prodotto di

• Institute of genetics and biophysics \"Adriano Buzzati Traverso\" (IGB) (Istituto)

Autore CNR

• DARIO ACAMPORA (Unità di personale interno)
• ANTONIO SIMEONE (Persona)

Incoming links:

Prodotto

• Institute of genetics and biophysics \"Adriano Buzzati Traverso\" (IGB) (Istituto)

Autore CNR di

• ANTONIO SIMEONE (Persona)
• DARIO ACAMPORA (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Genome biology (Rivista)