Effect of extremely low frequency magnetic fields on calpain activation. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Effect of extremely low frequency magnetic fields on calpain activation. (Articolo in rivista) (literal)

Anno

• 2006-01-01T00:00:00+01:00 (literal)

Alternative label

• Salamino F, Minafra R, Grano V, Diano N, Mita DG, Pontremoli S, Melloni E. (2006)
  Effect of extremely low frequency magnetic fields on calpain activation.
  in Bioelectromagnetics
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Salamino F, Minafra R, Grano V, Diano N, Mita DG, Pontremoli S, Melloni E. (literal)

Pagina inizio

• 43 (literal)

Pagina fine

• 50 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 27 (literal)

Rivista

• Bioelectromagnetics (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1Department of Experimental Medicine-Biochemistry Section, and Centre of Excellence for Biomedical Research, University of Genoa, Viale Benedetto XV, Genoa, Italy 2Department of Experimental Medicine, Second University of Naples, Via S.M. di Costantinopoli, Naples, Italy 3Institute of Genetics and Biophysics A. Buzzati Traverso of CNR, Via G. Marconi, Naples, Italy (literal)

Titolo

• Effect of extremely low frequency magnetic fields on calpain activation. (literal)

Abstract

• The effects of low intensity, low frequency magnetic fields (MFs) on catalytic activity of the calcium dependent protease calpain was determined following the enzyme activation both in in vitro and in vivo conditions. We have observed that a 0.3 mT MF induces a significant increase in the requirement of the protease for this metal ion. This change is detectable at low [Ca2+] and disappears when the level of Ca2+ is raised to saturating amounts. The observed effects are not due to transient MF- induced conformational changes occurring in calpain, but to direct effects of the MF on Ca2+ ions, which become less available for the binding sites present in calpain. Altogether, these results indicate that exposure to low intensity, low frequency MFs alters the intracellular Ca2+ availability, thereby modifying the related cell response. (literal)

Prodotto di

• Metodologie genomiche per le produzioni ecosostenibili e la tutela della salute (AG.P01.021.001) (Modulo)
• Istituto di genetica e biofisica \"Adriano Buzzati Traverso\" (IGB) (Istituto)

Autore CNR

• NADIA DIANO (Persona)
• DAMIANO GUSTAVO MITA (Unità di personale esterno)

Incoming links:

Autore CNR di

• DAMIANO GUSTAVO MITA (Unità di personale esterno)
• NADIA DIANO (Persona)

Prodotto

• Istituto di genetica e biofisica \"Adriano Buzzati Traverso\" (IGB) (Istituto)
• Metodologie genomiche per le produzioni ecosostenibili e la tutela della salute (AG.P01.021.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Bioelectromagnetics (Rivista)