http://www.cnr.it/ontology/cnr/individuo/prodotto/ID260871
Do COPD severity parameters predict mood disorders? (Contributo in atti di convegno)
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- Do COPD severity parameters predict mood disorders? (Contributo in atti di convegno) (literal)
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- 2013-01-01T00:00:00+01:00 (literal)
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Giuseppina Cuttitta, Palma Audino, Pietro Alfano, Salvatore Bucchieri, Mario Raphael Melis, and Fabio Cibella (2013)
Do COPD severity parameters predict mood disorders?
in European Respiratory Society, Barcelona Spain, 7-11 september 2013
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- Giuseppina Cuttitta, Palma Audino, Pietro Alfano, Salvatore Bucchieri, Mario Raphael Melis, and Fabio Cibella (literal)
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- Titolo
- Do COPD severity parameters predict mood disorders? (literal)
- Abstract
- Do COPD severity parameters predict mood disorders?
Giuseppina Cuttitta, Palma Audino, Pietro Alfano, Salvatore Bucchieri, Mario
Raphael Melis, Fabio Cibella.
Institute of Biomedicine and Molecular Immunology, National Research
Council of Italy, Palermo, Italy
We evaluated the mood states disorders in COPD patients and their relationship
with COPD severity parameters. We studied 60 consecutive stable COPD
outpatients (39 M; aged 53-91) and 30 subjects without respiratory disease
(control group) (14 M; aged 50-86). All subjects performed a spirometry and a
six minutes walking test (6'WT). Dyspnea perception was evaluated by modifi ed
Medical Research Council questionnaire (mMRC). Depressive and anxious
symptoms were investigated by Beck Depression Inventory-II and Stay Y,
respectively. The COPD patients were classifi ed on the basis of guidelines: 30
in group A, 8 in B, 13 in C, and 9 in D. The prevalence of depressive symptoms
in COPD patients and in controls was 28% and 23%, respectively (NS). No
signifi cant difference was found between groups for depression severity.
Among COPD patients, depressive symptoms distribution was: 5 in categorie A,
4 in B, 2 in C and 6 in D (p=.034).
A higher prevalence of depressive symptoms and higher severity levels were
found in B+D when compared to A+C subjects (p<0.0001). No difference was
found between A+B vs C+D subjects.
6'WT and mMRC were inversely related only in COPD patients (p<0.0001). The
mMRC was signifi cant different between groups (p=.022).
mMRC and depression were directly correlated (p<0.001). No association was
found between depression and GOLD stages, exacerbation in the last year.
Anxiety prevalence was not different between groups. Anxiety was not associated
with mMRC, GOLD stages, exacerbation in the last year.
We conclude that, among individual parameters of COPD severity, only mMRC
score is a good, strong and direct predictor of depression in COPD patients.
Depressive symptoms should be investigated in COPD when mMRC score is
high. (literal)
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