http://www.cnr.it/ontology/cnr/individuo/prodotto/ID260095
Antimony-Based Therapy of Leishmaniases, Molecular and Cellular Rationale. (Contributo in volume (capitolo o saggio))
- Type
- Label
- Antimony-Based Therapy of Leishmaniases, Molecular and Cellular Rationale. (Contributo in volume (capitolo o saggio)) (literal)
- Anno
- 2013-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1007/978-1-4614-1533-6 (literal)
- Alternative label
Colotti G; Ilari A (2013)
Antimony-Based Therapy of Leishmaniases, Molecular and Cellular Rationale.
Springer, New York (Stati Uniti d'America) in Encyclopedia of Metalloproteins, 2013
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Colotti G; Ilari A (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#titoloVolume
- Encyclopedia of Metalloproteins (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- IBPM Istituto Biologia e Patologia Molecolari CNR (literal)
- Titolo
- Antimony-Based Therapy of Leishmaniases, Molecular and Cellular Rationale. (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#isbn
- 978-1-4614-1532-9 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autoriVolume
- Robert H Kretsinger; Vladimir N Uversky; E A Permi?a?kov (literal)
- Abstract
- Pentavalent antimonials have been used for decades as
first-line compounds against leishmaniasis. The search
for the molecular basis of antimony-based treatment
against the parasite has long time eluded all investigators'
efforts. In the last two decades, many causes of
both antimonials action and resistance toward these
drugs on a molecular level have been identified. Both
mechanisms of action and of resistance are multifactorial,
the first depending on the effect on different
targets, and the second on different strategies used by
the parasite to escape the killing actions of antimonials. (literal)
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