Effects of rhodamine 123 in the dark and after irradiation on mitochondrial energy metabolism. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Effects of rhodamine 123 in the dark and after irradiation on mitochondrial energy metabolism. (Articolo in rivista) (literal)

Anno

• 1992-01-01T00:00:00+01:00 (literal)

Alternative label

• ATLANTE A, PASSARELLA S, MORENO G, SALET C (1992)
  Effects of rhodamine 123 in the dark and after irradiation on mitochondrial energy metabolism.
  in Photochemistry and photobiology
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• ATLANTE A, PASSARELLA S, MORENO G, SALET C (literal)

Pagina inizio

• 471 (literal)

Pagina fine

• 478 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 56 (literal)

Rivista

• Photochemistry and photobiology (Rivista)

Note

• PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Centro di Studio sui Mitocondri e Metabolismo Energetico C.N.R., Via Amendola 165/A, 70126 Bari, Italy Dipartimento di Scienze Animali, Vegetali e dell'Ambiente, Università del Molise, Via Cavour 50, 86100 Campobasso, Italy Laboratoire de Biophysique, INSERM U 201 et CNRS URA 481, Muséum National d'Histoire Naturelle, 43 rue Cuvier, 75231 Paris Cédex 05, France (literal)

Titolo

• Effects of rhodamine 123 in the dark and after irradiation on mitochondrial energy metabolism. (literal)

Abstract

• Isolated rat liver mitochondria have been used to study the mechanism of toxicity of Rhodamine 123 (Rho 123) in the dark and after irradiation with visible light. We report an inhibition of adenosine 5'-diphosphate phosphorylation which is increased after illumination. In the dark, the first steps of the phosphorylation process (i.e. the entry of substrates into the matrix, the electron transport to oxygen and the creation of the proton gradient) as well as ATPase activity are not significantly perturbed at Rho 123 concentration below 10 micrograms/mL. In contrast, the movements of the phosphate compounds are drastically impaired. Irradiation strengthens the detrimental effects in an oxygen dependent process. The nature of the noxious transient species is not clearly established, but it is suggested that singlet oxygen could be responsible for the observed damage. (literal)

Prodotto di

• Institute of biomembrane and bioenergetics (IBBE) (Istituto)
• Interrelazione nucleo/citoplasma/mitocondri nell'omeostasi cellulare. (SV.P15.003.001) (Modulo)

Autore CNR

• ANNA ATLANTE (Unità di personale interno)

Incoming links:

Prodotto

• Institute of biomembrane and bioenergetics (IBBE) (Istituto)
• Interrelazione nucleo/citoplasma/mitocondri nell'omeostasi cellulare. (SV.P15.003.001) (Modulo)

Autore CNR di

• ANNA ATLANTE (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Photochemistry and photobiology (Rivista)