http://www.cnr.it/ontology/cnr/individuo/prodotto/ID254446
ENHANCED RESPONSE TO DAUNOMYCIN OF NORMAL, TUMOR AND METASTATIC CELL-LINES VIA DRUG PHOTOACTIVATION (Articolo in rivista)
- Type
- Label
- ENHANCED RESPONSE TO DAUNOMYCIN OF NORMAL, TUMOR AND METASTATIC CELL-LINES VIA DRUG PHOTOACTIVATION (Articolo in rivista) (literal)
- Anno
- 1993-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1111/j.1751-1097.1993.tb09223.x (literal)
- Alternative label
ANDREONI, A 1; COLASANTI, A 3; KISSLINGER, A 2; MASTROCINQUE, M 2; PORTELLA, G 2; RICCIO, P 3; ROBERTI, G 3 (1993)
ENHANCED RESPONSE TO DAUNOMYCIN OF NORMAL, TUMOR AND METASTATIC CELL-LINES VIA DRUG PHOTOACTIVATION
in Photochemistry and photobiology; J. Wiley & sons, New York (Stati Uniti d'America)
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- ANDREONI, A 1; COLASANTI, A 3; KISSLINGER, A 2; MASTROCINQUE, M 2; PORTELLA, G 2; RICCIO, P 3; ROBERTI, G 3 (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- [ 1 ] UNIV NAPLES,DIPARTIMENTO BIOL & PATOL CELLULARE & MOLEC,I-80131 NAPLES,ITALY
[ 2 ] FDN SEN G PASCALE,IST NAZL STUDIO & CURA TUMORI,I-80131 NAPLES,ITALY
[ 3 ] UNIV NAPLES,DIPARTIMENTO SCI FIS,I-80125 NAPLES,ITALY (literal)
- Titolo
- ENHANCED RESPONSE TO DAUNOMYCIN OF NORMAL, TUMOR AND METASTATIC CELL-LINES VIA DRUG PHOTOACTIVATION (literal)
- Abstract
- We have compared the cytotoxicity of daunomycin in vitro to highly differentiated normal epithelial cells (Fisher rat thyroid cells, FRTL-5) and to two neoplastic cell lines, a thyroid carcinoma (TK-6) and its lung metastasis (MPTK-6). Whereas the cell lines are equally sensitive to the drug in the dark, if irradiated during incubation with daunomycin (86 J/cm2 at 488 nm), they become more and differently sensitive. Namely, the drug doses producing 50% mortality decrease by factors of about 22, 28 and 16 for FRTL-5, TK-6 and MPTK-6 cell lines, respectively. This result correlates with differences in drug uptake and resistance observed in the normal and neoplastic cell lines. (literal)
- Editore
- Prodotto di
- Autore CNR
Incoming links:
- Autore CNR di
- Prodotto
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
- Editore di