http://www.cnr.it/ontology/cnr/individuo/prodotto/ID250546
Cell type-specific interactions of transcription factors with a housekeeping promoter in vivo (Articolo in rivista)
- Type
- Label
- Cell type-specific interactions of transcription factors with a housekeeping promoter in vivo (Articolo in rivista) (literal)
- Anno
- 1993-01-01T00:00:00+01:00 (literal)
- Alternative label
Stapleton G, Somma MP, Lavia P. (1993)
Cell type-specific interactions of transcription factors with a housekeeping promoter in vivo
in Nucleic acids research; Oxford University Press, Oxford (Regno Unito)
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Stapleton G, Somma MP, Lavia P. (literal)
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- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- AFRC Centre for Genome Research, University of Edinburgh, UK (literal)
- Titolo
- Cell type-specific interactions of transcription factors with a housekeeping promoter in vivo (literal)
- Abstract
- Mammalian housekeeping promoters represent a class of regulatory elements different from those of tissues-specific genes, lacking a TATA box and associated with CG-rich DNA. We have compared the organization of the housekeeping Htf9 promoter in different cell types by genomic footprinting. The sites of in vivo occupancy clearly reflected local combinations of tissue-specific and ubiquitous binding factors. The flexibility of the Htf9 promoter in acting as the target of cell-specific combinations of factors may ensure ubiquitous expression of the Htf9-associated genes. (literal)
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