http://www.cnr.it/ontology/cnr/individuo/prodotto/ID249040
THE ARGO_SITES: AN ANALYSIS AND RECOGNITION OF THE TRANSCRIPTION FACTOR BINDING SITES BASED ON SETS OF DEGENERATE OLIGONUCLEOTIDE MOTIFS (Contributo in atti di convegno)
- Type
- Label
- THE ARGO_SITES: AN ANALYSIS AND RECOGNITION OF THE TRANSCRIPTION FACTOR BINDING SITES BASED ON SETS OF DEGENERATE OLIGONUCLEOTIDE MOTIFS (Contributo in atti di convegno) (literal)
- Anno
- 2004-01-01T00:00:00+01:00 (literal)
- Alternative label
OV Vishnevsky, EV Ignatieva, P Arrigo (2004)
THE ARGO_SITES: AN ANALYSIS AND RECOGNITION OF THE TRANSCRIPTION FACTOR BINDING SITES BASED ON SETS OF DEGENERATE OLIGONUCLEOTIDE MOTIFS
in The Fourth International Conference on Bioinformatics of Genome Regulation and Structure (BGRS'2004), Novosibirsk, July 25-30
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- OV Vishnevsky, EV Ignatieva, P Arrigo (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Siberian Branch of Russian Academy of Science
CNR ISMAC (literal)
- Titolo
- THE ARGO_SITES: AN ANALYSIS AND RECOGNITION OF THE TRANSCRIPTION FACTOR BINDING SITES BASED ON SETS OF DEGENERATE OLIGONUCLEOTIDE MOTIFS (literal)
- Abstract
- Motivation: The transcription factor binding sites (TFBS) are the critical determinants of the
assembly and positioning of the basal transcription complex, thereby providing the tissue- and
stage-specificity of transcription in the eukaryotic genes. Development of new methods to analyse
and recognize the TFDSs are required for clarifying the structural - functional organization of
the regulatory regions of the eukaryotic genes and improving our understanding of the mechanisms
underlying genetic information expression.
Results: Based on the method we previously designed for identifying sets of degenerate
oligonucleotide motifs, 17 TFBS samples of eukaryotes were analyzed. For the analyzed samples,
sets of significant motifs were built, and the specific features of the nucleotide context at the
5'- and 3'- flanking regions were identified for the sites. The ARGO_Sites program for the
recognition of the identified TFBSs on the basis of the identified motifs was developed.
Availability: http://wwwmgs.bionet.nsc.ru/mgs/programs/argosites/ (literal)
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