A Study for the Cause of Ferulic Acid-Induced Quenching of Tyrosine Fluorescence and Whether it is a Reliable Marker of Intermolecular Interactions or Not (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• A Study for the Cause of Ferulic Acid-Induced Quenching of Tyrosine Fluorescence and Whether it is a Reliable Marker of Intermolecular Interactions or Not (Articolo in rivista) (literal)

Anno

• 2013-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1007/s10895-013-1180-3 (literal)

Alternative label

• Sgarbossa A, Lenci F (2013)
  A Study for the Cause of Ferulic Acid-Induced Quenching of Tyrosine Fluorescence and Whether it is a Reliable Marker of Intermolecular Interactions or Not
  in Journal of fluorescence; Springer, New York (Stati Uniti d'America)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Sgarbossa A, Lenci F (literal)

Pagina inizio

• 561 (literal)

Pagina fine

• 567 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://link.springer.com/article/10.1007%2Fs10895-013-1180-3 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 23 (literal)

Rivista

• Journal of fluorescence (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 3 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Istituto di Biofisica del CNR, Pisa, Italy (literal)

Titolo

• A Study for the Cause of Ferulic Acid-Induced Quenching of Tyrosine Fluorescence and Whether it is a Reliable Marker of Intermolecular Interactions or Not (literal)

Abstract

• Intrinsic fluorescence of peptides and proteins is extensively used to monitor their specific interactions with several natural and synthetic molecules known to have wide-ranging beneficial or detrimental effects on health. A consequence of these interactions would be a significant decrease of the fluorescence emission intensity of Tyrosine (Tyr) and/or Tryptophan (Trp) residues in the protein due to structural rearrangements of proteic microenvironment. However fluorescence quenching can be also caused by \"trivial\" artefacts. In this study we examined the effect of Ferulic acid (FA) on Tyr fluorescence. FA is a natural anti-oxidant suggested to bind to and to modify the structural properties of several proteins thus altering their biological activities. Fluorescence spectroscopy experiments on Tyr and on proteins containing Tyr and no Trp like beta amyloid peptides and Insulin were performed. Our results suggest that Tyr fluorescence loss can mainly result from an inner filter effect rather than from specific interactions with FA. (literal)

Editore

• Springer (Editore)

Prodotto di

• Processi Fotoindotti in Biomolecole e Cellule (MD.P01.003.001) (Modulo)
• Istituto di biofisica (IBF) (Istituto)

Autore CNR

• FRANCESCO LENCI (Unità di personale esterno)
• ANTONELLA SGARBOSSA (Unità di personale interno)

Insieme di parole chiave

• Parole chiave di "A Study for the Cause of Ferulic Acid-Induced Quenching of Tyrosine Fluorescence and Whether it is a Reliable Marker of Intermolecular Interactions or Not" (Insieme di parole chiave)

Incoming links:

Prodotto

• Istituto di biofisica (IBF) (Istituto)
• Processi Fotoindotti in Biomolecole e Cellule (MD.P01.003.001) (Modulo)

Autore CNR di

• ANTONELLA SGARBOSSA (Unità di personale interno)
• FRANCESCO LENCI (Unità di personale esterno)

Editore di

• Springer (Editore)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of fluorescence (Rivista)

Insieme di parole chiave di

• Parole chiave di "A Study for the Cause of Ferulic Acid-Induced Quenching of Tyrosine Fluorescence and Whether it is a Reliable Marker of Intermolecular Interactions or Not" (Insieme di parole chiave)