Scar extent, left ventricular end-diastolic volume and wall motion abnormalities identify high-risk patients with previous myocardial infarction: a multiparametric approach for prognostic stratification (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Scar extent, left ventricular end-diastolic volume and wall motion abnormalities identify high-risk patients with previous myocardial infarction: a multiparametric approach for prognostic stratification (Articolo in rivista) (literal)

Anno

• 2013-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1093/eurheartj/ehs037 (literal)

Alternative label

• Gianluca Di Bella, Valeria Siciliano, Giovanni Donato Aquaro, Sabrina Molinaro, Massimo Lombardi, Scipione Carerj, Patrizia Landi, Daniele Rovai, and Alessandro Pingitore (2013)
  Scar extent, left ventricular end-diastolic volume and wall motion abnormalities identify high-risk patients with previous myocardial infarction: a multiparametric approach for prognostic stratification
  in Indo- European heart journal
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Gianluca Di Bella, Valeria Siciliano, Giovanni Donato Aquaro, Sabrina Molinaro, Massimo Lombardi, Scipione Carerj, Patrizia Landi, Daniele Rovai, and Alessandro Pingitore (literal)

Pagina inizio

• 104 (literal)

Pagina fine

• 1011 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.ncbi.nlm.nih.gov/pubmed/22368185 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 34 (literal)

Rivista

• Indo- European heart journal (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 8 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 2 (literal)

Note

• PubMed (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• CNR, Institute of Clinical Physiology, Pisa, Italy. Clinical and Experimental Department of Medicine and Pharmacology, University of Messina, Messina, Italy. Fondazione Toscana G. Monasterio, Pisa, Italy. (literal)

Titolo

• Scar extent, left ventricular end-diastolic volume and wall motion abnormalities identify high-risk patients with previous myocardial infarction: a multiparametric approach for prognostic stratification (literal)

Abstract

• AIMS: We sought to investigate whether combining left ventricular (LV) volumes, regional wall motion abnormalities, and scar tissue extent obtained by cardiac magnetic resonance (CMR) improves risk stratification of patients with previous myocardial infarction (MI). METHODS AND RESULTS: In 231 consecutive patients (age 64 ± 11 years, males 89%) with previous MI, we quantified LV volumes and regional wall motion abnormalities by cine CMR, and measured the extent of the infarction scar by late gadolinium enhancement (LGE). During follow-up (median, 3.2 years) cardiac events (cardiac death or appropriate intra-cardiac defibrillator shocks) occurred in 19 patients. After adjustment for age, an extent of LGE >12.7%, an LV end-diastolic volume >105 mL/m(2), and a wall motion score index >1.7 were independent associated with adverse cardiac events at multivariate analysis (P < 0.05, P < 0.001, and P < 0.01, respectively). The patients with none of these factors, and those with one or two factors, showed a lower risk of cardiac events [hazard ratio (HR) = 0.112, P < 0.01 and HR = 0.261, P < 0.05] than those with three factors. The cumulative event-rate estimated at 4 years was 29.6% in patients with all three factors, 7.7% in those with one or two factors, and 3.5% in patients with none of these factors. CONCLUSION: A multiparametric CMR approach, which includes the measure of scar tissue extent, LV end-diastolic volume and regional wall motion abnormalities, improves risk stratification of patients with previous MI. (literal)

Prodotto di

• Istituto di fisiologia clinica (IFC) (Istituto)

Autore CNR

• DANIELE ROVAI (Persona)
• ALESSANDRO PINGITORE (Persona)
• PATRIZIA LANDI (Unità di personale interno)

Insieme di parole chiave

• Keywords of "Scar extent, left ventricular end-diastolic volume and wall motion abnormalities identify high-risk patients with previous myocardial infarction: a multiparametric approach for prognostic stratification" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• ALESSANDRO PINGITORE (Persona)
• DANIELE ROVAI (Persona)
• PATRIZIA LANDI (Unità di personale interno)

Prodotto

• Istituto di fisiologia clinica (IFC) (Istituto)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Indo- European heart journal (Rivista)

Insieme di parole chiave di

• Keywords of "Scar extent, left ventricular end-diastolic volume and wall motion abnormalities identify high-risk patients with previous myocardial infarction: a multiparametric approach for prognostic stratification" (Insieme di parole chiave)