Crystallization and preliminary X-ray diffraction studies of a monooxigenase from Streptomyces coelicolor A3(2) involved in the biosynthesis of the polyketide actinorhodin (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Crystallization and preliminary X-ray diffraction studies of a monooxigenase from Streptomyces coelicolor A3(2) involved in the biosynthesis of the polyketide actinorhodin (Articolo in rivista) (literal)

Anno

• 2000-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1107/S0907444900001189 (literal)

Alternative label

• Kendrew, SG; Federici, L; Savino, C; Miele, A; Marsh, ENG; Vallone, B (2000)
  Crystallization and preliminary X-ray diffraction studies of a monooxigenase from Streptomyces coelicolor A3(2) involved in the biosynthesis of the polyketide actinorhodin
  in Acta crystallographica. Section D, Biological crystallography.; MUNKSGAARD INT PUBL LTD, COPENHAGEN (Danimarca); Wiley-Blackwell Publishing, Inc., Malden (Stati Uniti d'America)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Kendrew, SG; Federici, L; Savino, C; Miele, A; Marsh, ENG; Vallone, B (literal)

Pagina inizio

• 481 (literal)

Pagina fine

• 483 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 56 (literal)

Rivista

• Acta crystallographica. Section D, Biological crystallography. (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 4 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• [ 1 ] Univ Rome La Sapienza, Dipartimento Sci Biochim, I-00185 Rome, Italy [ 2 ] Univ Rome La Sapienza, CNR, Ctr Biol Mol, I-00185 Rome, Italy [ 3 ] Biot Technol Ltd, Cambridge CB3 0DJ, England [ 4 ] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA (literal)

Titolo

• Crystallization and preliminary X-ray diffraction studies of a monooxigenase from Streptomyces coelicolor A3(2) involved in the biosynthesis of the polyketide actinorhodin (literal)

Abstract

• The aromatic monooxygenase ActVA-Orf6 from Streptomyces coelicolor A3(2) that catalyses an unusual oxidation on the actinorhodin biosynthetic pathway has been crystallized. The crystals diffract to 1.73 Angstrom and belong to space group P2(1)2(1)2(1), with unit-cell parameters a = 46.95, b = 59.29, c = 71.67 Angstrom. Solvent-content (44%) and self-rotation function calculations predict the presence of two molecules in the asymmetric unit. Structure determination should provide further insight into the enzyme mechanism and aid in the design of biosynthetic pathways to produce new polyketide natural products with novel functionality. (literal)

Editore

• MUNKSGAARD INT PUBL LTD (Editore)
• Wiley-Blackwell Publishing, Inc. (Editore)

Prodotto di

• Institute of molecular biology and pathology (IBPM) (Istituto)
• Biologia strutturale e bioinformatica: struttura-funzione, dinamica e riconoscimento in proteine (SV.P14.008.001) (Modulo)

Autore CNR

• CARMELINDA SAVINO (Persona)
• BEATRICE VALLONE (Unità di personale esterno)

Insieme di parole chiave

• Keywords of "Crystallization and preliminary X-ray diffraction studies of a monooxigenase from Streptomyces coelicolor A3(2) involved in the biosynthesis of the polyketide actinorhodin" (Insieme di parole chiave)

Incoming links:

Prodotto

• Institute of molecular biology and pathology (IBPM) (Istituto)
• Biologia strutturale e bioinformatica: struttura-funzione, dinamica e riconoscimento in proteine (SV.P14.008.001) (Modulo)

Autore CNR di

• CARMELINDA SAVINO (Persona)
• BEATRICE VALLONE (Unità di personale esterno)

Editore di

• Wiley-Blackwell Publishing, Inc. (Editore)
• MUNKSGAARD INT PUBL LTD (Editore)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Acta crystallographica. Section D, Biological crystallography. (Rivista)

Insieme di parole chiave di

• Keywords of "Crystallization and preliminary X-ray diffraction studies of a monooxigenase from Streptomyces coelicolor A3(2) involved in the biosynthesis of the polyketide actinorhodin" (Insieme di parole chiave)