http://www.cnr.it/ontology/cnr/individuo/prodotto/ID24309
Heart-type fatty acid binding protein is an early marker of myocardial damage after radiofrequency catheter ablation (Articolo in rivista)
- Type
- Label
- Heart-type fatty acid binding protein is an early marker of myocardial damage after radiofrequency catheter ablation (Articolo in rivista) (literal)
- Anno
- 2010-01-01T00:00:00+01:00 (literal)
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Giannessi D.; Piacenti M.; Maltinti M.; Rossi A.; Di Cecco P.; Startari U.; Cabiati M.; Panchetti L.; Del Ry S.; Morales M. A. (literal)
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
- In: Clinical Biochemistry, vol. 43 (15) pp. 1241 - 1245. Elsevier, 2010. (literal)
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- CNR-IFC, Pisa, USL, Pisa, Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy, Scuola Superiore Sant'Anna, Pisa (Italy) (literal)
- Titolo
- Heart-type fatty acid binding protein is an early marker of myocardial damage after radiofrequency catheter ablation (literal)
- Abstract
- OBJECTIVES: Radiofrequency (RF) ablation of arrhythmias induces myocardial damage and release of biomarkers. This study aimed to assess the kinetics of heart-type fatty acid-binding protein (h-FABP), a cytosolic protein released after myocardial injury incurred by both atrial and ventricular RF ablation, compared to other markers of myocardial injury. DESIGN AND METHODS: h-FABP, cTnI, CK-MB(mass) and myoglobin were evaluated in 30 patients with atrial or ventricular tachyarrhythmias before, immediately after and at 3, 6 and 24h after the procedure. RESULTS: h-FABP increased immediately after the procedure in all subjects (6.6 ± 1.2 ¼g/L vs 2.7 ± 0.3, p0.001) but increased significantly only in ventricular ablations. The peak of h-FABP significantly correlates with the values of time for mean power of RF application in both the entire patient cohort and in ventricular ablations. CONCLUSIONS: h-FABP may be an early parameter for monitoring RF-induced lesions and the site of ablation was relevant for biomarker increase. (literal)
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