Sequence and gene content in 52 kb including and centromeric to the G6PD gene in Xq28. (Articolo in rivista)

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  • Sequence and gene content in 52 kb including and centromeric to the G6PD gene in Xq28. (Articolo in rivista) (literal)
Anno
  • 1995-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.3109/10425179509074693 (literal)
Alternative label
  • Zollo M, Mazzarella R, Bione S, Toniolo D, Schlessinger D, D'Urso M, Chen EY. (1995)
    Sequence and gene content in 52 kb including and centromeric to the G6PD gene in Xq28.
    in DNA sequence (Print); Harwood Academic Publishers, Reading (Regno Unito)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Zollo M, Mazzarella R, Bione S, Toniolo D, Schlessinger D, D'Urso M, Chen EY. (literal)
Pagina inizio
  • 1 (literal)
Pagina fine
  • 11 (literal)
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  • http://pubget.com/paper/pgtmp_cf945d6d2f668f91a5330cbb9db35cf5/sequence-and-gene-content-in-52-kb-including-and-centromeric-to-the-g6pd-gene-in-xq28 (literal)
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  • 6 (literal)
Rivista
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  • 11 (literal)
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  • 1 (literal)
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  • PubMe (literal)
  • ISI Web of Science (WOS) (literal)
  • Scopu (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Advanced Center for Genetic Technology, Applied Biosystems Division of Perkin-Elmer Corp., Foster City, CA 94404, USA; Istituto di Genetica, Biochimica ed evoluzionistica, CNR, Pavia, Italy; Istituto Internazionale di Genetica e Biofisica, CNR, Napoli, Italy. (literal)
Titolo
  • Sequence and gene content in 52 kb including and centromeric to the G6PD gene in Xq28. (literal)
Abstract
  • A cosmid containing 36.4 kb of high GC human DNA centromeric to the G6PD gene has been analyzed. The sequence was 99.9% precise, based on the comparison of 4.3 kb that overlaps an earlier analysis of 20.1 kb containing G6PD. Properties of the entire 52 kb region that may be characteristic of high GC portions of the genome include a very high density of sixty-two half or full Alu sequences, or 1.2/kb, and an absence of L1 sequences. Other highly repetitive sequences include 11 MER sequences, one of them interrupted at two positions by groups of 3 Alu elements. In segments of unique sequence, computer-aided analysis predicted three possible genes, one of which has thus far been confirmed by the recovery of a corresponding cDNA, both by a direct hybridization method and by a PCR-based method based on a primer pair inferred from the genomic sequence. The cDNA has been sequenced, and is completely concordant with counterpart genomic sequence; it has no resemblance to any previously described gene. (literal)
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