http://www.cnr.it/ontology/cnr/individuo/prodotto/ID24221
Susceptibility Factors to Ozone-related Mortality (Articolo in rivista)
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- Susceptibility Factors to Ozone-related Mortality (Articolo in rivista) (literal)
- Anno
- 2010-01-01T00:00:00+01:00 (literal)
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- Stafoggia M.; Forastiere F.; Faustini A.; Biggeri A.; Bisanti L.; Cadum E.; Cernigliaro A.; Mallone S.; Pandolfi P.; Serinelli M.; Tessari R.; Vigotti M. A.; Perucci C. A.; Baldacci S. I. C.; Viegi G. I. C.; Epiair G. (literal)
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- In: American Journal of Respiratory and Critical Care Medicine, vol. 182 pp. 376 - 384. atsjournals, 2010. (literal)
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- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Department of Epidemiology, Rome/E Local Health Authority, Rome (Italy), Department of Statistics, University of Florence, Florence (Italy) - Unit of Biostatistics, Istituto per lo Studio e la Prevenzione Oncologica, Florence (Italy), Epidemiological Service, Local Health Authority, Milan, Italy, Epidemiological Services, Regional Environmental Protection Agency, Piedmont, Turin, Italy, Epidemiological Observatory, Regional Health Authority, Palermo, Italy, Centre for Cancer Prevention, Florence, Italy, Epidemiological Observatory, Local Health Authority, Bologna, Italy, National Research Council, Lecce, Italy, Department of Environmental Medicine and Public Health, University of Padua, Padua, Italy, Department of Biology, University of Pisa, Pisa, Italy, CNR-IFC, Pisa (literal)
- Titolo
- Susceptibility Factors to Ozone-related Mortality (literal)
- Abstract
- Rationale: Acute effects of ozone on mortality have been extensively documented in clinical and epidemiological research. However, only a few studies have focusedonsubgroupsof the population especially vulnerable to these effects. Objectives: To estimate the association between exposure to ozone and cause-specific mortality, and to evaluate whether individual sociodemographic characteristics or chronic conditions confer greater susceptibility to the adverse effects of ozone. Methods: A case-crossover analysis was conducted in 10 Italian cities. Data on mortality were collected for the period 2001 to 2005 (April- September) for 127,860 deceased subjects. Information was retrievedon cause of death, sociodemographic characteristics, chronic conditions from previous hospital admissions, and location of death. Daily ozone concentrations were collected from background fixed monitors. Measurements and Main Results: We estimated a 1.5% (95% confidence interval [CI], 0.9-2.1) increase in total mortality for a 10mg/m3 increase in ozone (8-h, lag 0-5). The effect lasted several days for total, cardiac and respiratory mortality (lag 0-5), and it was delayed for cerebrovascular deaths (lag 3-5). In the subgroup analysis, the effect was more pronounced in people older than 85 years of age (3.5%; 95% CI, 2.4-4.6) than in 35- to 64-year-old subjects (0.8%; 95% CI,20.8 to 2.5), in women (2.2%; 95% CI, 1.4-3.1) than in men (0.8%; 95% CI, 20.1 to 1.8), and for out-of-hospital deaths (2.1%; 95% CI, 1.0-3.2), especially among patients with diabetes (5.5%; 95% CI, 1.4-9.8). Conclusions:Agreater vulnerability of elderly people andwomenwas indicated; subjects who died at home and had diabetes emerged as especially affected. (literal)
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