Multicenter Validation of the Magnetic Resonance T2* Technique for Segmental and Global Quantification of Myocardial Iron (Articolo in rivista)

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  • Multicenter Validation of the Magnetic Resonance T2* Technique for Segmental and Global Quantification of Myocardial Iron (Articolo in rivista) (literal)
Anno
  • 2009-01-01T00:00:00+01:00 (literal)
Alternative label
  • Ramazzotti A, Pepe A, Positano V, Rossi G, De Marchi D, Brizi MG, Luciani A, Midiri M, Sallustio G, Valeri G, Caruso V, Centra M, Cianciulli P, De Sanctis V, Maggio A, Lombardi M. (2009)
    Multicenter Validation of the Magnetic Resonance T2* Technique for Segmental and Global Quantification of Myocardial Iron
    in Journal of magnetic resonance imaging (Print); WILEY-LISS, DIV JOHN WILEY & SONS INC, 111 RIVER ST, HOBOKEN, NJ 07030 (Stati Uniti d'America)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Ramazzotti A, Pepe A, Positano V, Rossi G, De Marchi D, Brizi MG, Luciani A, Midiri M, Sallustio G, Valeri G, Caruso V, Centra M, Cianciulli P, De Sanctis V, Maggio A, Lombardi M. (literal)
Pagina inizio
  • 62 (literal)
Pagina fine
  • 68 (literal)
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  • 30 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
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  • 1MRI Laboratory, \"G Monasterio\" Foundation and Institute of Clinical Physiology, Pisa, Italy. 2Epidemiology and Biostatistics Unit, Institute of Clinical Physiology, Pisa, Italy. 3Department of Radiology, Universita` Cattolica del Sacro Cuore, Roma, Italy. 4Department of Radiology, \"G Garibaldi\" Hospital, Catania, Italy. 5Department of Radiology, University of Palermo, Palermo, Italy. 6Department of Radiology, Universita` Cattolica del Sacro Cuore, Campobasso, Italy. 7Department of Radiology, University of Marche, Ancona, Italy. 8Department of Thalassemia, POU \"S. Luigi-Curro` \", Catania, Italy. 9Department of Microcitemia, \"Casa Sollievo della Sofferenza\" Hospital, San Giovanni Rotondo(FG), Italy. 10Department of Thalassemia, \"Sant'Eugenio Papa\" Hospital, Roma, Italy. 11Department of Thalassemia, \"S.Anna\" Hospital, Ferrara, Italy. 12Haematology II with Thalassemia, \"V. Cervello\" Hospital, Palermo, Italy. (literal)
Titolo
  • Multicenter Validation of the Magnetic Resonance T2* Technique for Segmental and Global Quantification of Myocardial Iron (literal)
Abstract
  • Purpose: To assess the transferability of the magnetic resonance imaging (MRI) multislice multiecho T2* technique for global and segmental measurement of iron overload in thalassemia patients. Materials and Methods: Multiecho T2* sequences were installed on six MRI scanners. Five healthy subjects (n ?30) were scanned at each site; five thalassemia major (TM) patients were scanned at the reference site and were rescanned locally (n ? 25) within 1 month. T2* images were analyzed using previously validated software. Results: T2* values of healthy subjects showed intersite homogeneity. On TM patients, for global heart T2* values the correlation coefficient was 0.97, coefficients of variation (CoVs) ranged from 0.04-0.12, and intraclass coefficients (ICCs) ranged from 0.94-0.99. The mean CoV and ICC for segmental T2* distribution were 0.198 and 88, respectively. Conclusion: The multislice multiecho T2* technique is transferable among scanners with good reproducibility. (literal)
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