http://www.cnr.it/ontology/cnr/individuo/prodotto/ID24190

Time course of carbon monoxide transfer factor after breath-hold diving (Articolo in rivista)

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Time course of carbon monoxide transfer factor after breath-hold diving (Articolo in rivista) (literal)

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Prediletto R, Fornai E, Catapano G, Carli C, Garbella E, Passera M, Cialoni D, Bedini R, L'Abbate A (2009)
Time course of carbon monoxide transfer factor after breath-hold diving
in Undersea & hyperbaric medicine
(literal)

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Prediletto R, Fornai E, Catapano G, Carli C, Garbella E, Passera M, Cialoni D, Bedini R, L'Abbate A (literal)

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Bedini Remo: Primo Ricercatore CNR, Istituto di Fisiologia Clinica, Pisa Fornai Edo CTER, Istituto di Fisiologia Clinica, CNR Passera Mirko, CTER, Istituto di Fisiologia Clinica, CNR Catapano Giosuè, Dirigente Medico, Fondazione CNR-Regione Toscana Gabriele Monasterio, Pisa L'Abbate Antonio, Associato Istituto di Fisiologia Clinica, Scuola Superiore S. Anna, Pisa Renato Prediletto, Primo Ricercatore, Istituto di Fisiologia Clinica del CNR (literal)

Titolo

Time course of carbon monoxide transfer factor after breath-hold diving (literal)

Abstract

Breath-hold divers may experience haemoptysis during diving. Central pooling of blood as well as compression of pulmonary gas content can damage the integrity of the blood-gas barrier, resulting in alveolar hemorrhage. The single-breath carbon monoxide test (DL,CO) was used to investigate the blood-gas barrier following diving. The study population consisted of 30 divers recruited from a training course. DL,CO levels were measured before diving and at 2, 10 and 25 min after the last of a series of four dives to depths of 10, 15, 20 and 30 m. When compared to pre-diving values, DL,CO values increased significantly at 2 min following diving in all subjects except one. Thereafter values progressively decreased toward baseline at 10 and 25 min in all subjects but one, while in four divers DL,CO values decreased below baseline. The early but transient increase in DL,CO levels shortly after diving supports the persistence of capillary pooling of red blood cells following emersion. Persistence at 25 min of high DL,CO values in one subject could be attributed by lung CT to extravasation of blood into the alveoli. Early or late DL,CO values >10% below baseline values suggest the presence of pulmonary edema. The relatively high prevalence of DL,CO alterations found suggests caution on the safety of breath-hold diving activities. (literal)

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