Paucity of anginal symptoms and stress-induced perfusion abnormalities in ischemic cardiomyopathy (Articolo in rivista)

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Label
  • Paucity of anginal symptoms and stress-induced perfusion abnormalities in ischemic cardiomyopathy (Articolo in rivista) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.nuclcard.2008.06.012 (literal)
Alternative label
  • Alessia Gimelli; Paolo Marzullo; Patrizia Landi; Antonio L'Abbate; Matteo Bottai; Daniele Rovai. (2008)
    Paucity of anginal symptoms and stress-induced perfusion abnormalities in ischemic cardiomyopathy
    in Journal of nuclear cardiology; Springer New York, New York (Stati Uniti d'America)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Alessia Gimelli; Paolo Marzullo; Patrizia Landi; Antonio L'Abbate; Matteo Bottai; Daniele Rovai. (literal)
Pagina inizio
  • 680 (literal)
Pagina fine
  • 686 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url
  • http://www.sciencedirect.com/science/article/pii/S1071358108002171 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 15 (literal)
Rivista
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  • In: Journal of Nuclear Cardiology, vol. 15 pp. 680 - 686. American Society of Nuclear Cardiology, 2008. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 7 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Istituto di Fisiologia Clinica del CNR, Pisa Scuola Superiore Sant'Anna, Pisa Department of Epidemiology and Biostatistics, University of South Carolina, Columbia, SC.c, USA (literal)
Titolo
  • Paucity of anginal symptoms and stress-induced perfusion abnormalities in ischemic cardiomyopathy (literal)
Abstract
  • Background. We sought to investigate whether the paucity of anginal symptoms in patients with ischemic cardiomyopathy reflects a reduction in the severity of stress-induced myocardial ischemia. Methods and Results. We selected 38 patients with coronary artery disease and severe left ventricular dysfunction (ejection fraction [EF] <25%) (group 1), who underwent stress gated single photon emission computed tomography. In parallel, we selected 2 groups of 38 patients with coronary artery disease and EF between 26% and 45% (group 2) or EF greater than 45% (group 3), matched to group 1 patients. Effort angina was less frequent in group 1 (29%) than in group 2 (50%) and group 3 (82%) (P ? .023). Stress-induced perfusion abnormalities, identified by the summed difference score (SDS), were less extensive in group 1 (mean SDS, 3 ? 3) than in group 2 (mean SDS, 6 ? 5) and group 3 (mean SDS, 8 ? 4) (P ? .019), whereas perfusion abnormalities at rest (summed rest score [SRS]) were more extensive in group 1 (mean SRS, 12 ? 4) than in group 2 (mean SRS, 6 ? 3) and group 3 (mean SRS, 3 ? 2) (P ? .015). Conclusion. The paucity of anginal symptoms in ischemic cardiomyopathy reflects a limited extent of stress-induced myocardial ischemia and a higher extent of necrosis. (literal)
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