http://www.cnr.it/ontology/cnr/individuo/prodotto/ID23981
C-type natriuretic peptide and its relation to non-invasive indices of left ventricular function in patients with chronic heart failure (Articolo in rivista)
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- Label
- C-type natriuretic peptide and its relation to non-invasive indices of left ventricular function in patients with chronic heart failure (Articolo in rivista) (literal)
- Anno
- 2008-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1016/j.peptides.2007.10.022 (literal)
- Alternative label
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Del Ry S.; Maltinti M.; Cabiati M.; Emdin M.; Giannessi D.; Morales M. A. (literal)
- Pagina inizio
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- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
- In: Peptides, vol. 29 pp. 79 - 82. Elsevier, 2008. (literal)
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- CNR-IFC, Pisa, IFC - Fondazione G. Monasterio Pisa (literal)
- Titolo
- C-type natriuretic peptide and its relation to non-invasive indices of left ventricular function in patients with chronic heart failure (literal)
- Abstract
- C-type natriuretic peptide (CNP) significantly increases in chronic heart failure (CHF)patients as a function of clinical severity. Aim of this study was to evaluate in CHF patients the relationship between circulating CNP concentrations and echo-Doppler conventional indices of left ventricular (LV) function as well as less load independent parameters as dP/dt. LV ejection fraction (EF), left ventricular end-diastolic dimension (LVEDD) and LV dP/dt were evaluated together with plasma CNP levels in 38 patients with CHF and in 63 controls. CNP levels resulted significantly higher in CHF patients than in controls (7.19 0.59 pg/ml vs. 2.52 0.12 pg/ml, p 0.0001). A significant correlation between dP/dt and CNP levels (r 600, n = 13): 8.46 0.69 and 4.75 0.75 pg/ml, respectively, p 0.001. This is the first study that reports a correlation between CNP and dP/ dt in CHF patients, thus suggesting a possible role on cardiac contractility. (literal)
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