C-type natriuretic peptide and its relation to non-invasive indices of left ventricular function in patients with chronic heart failure (Articolo in rivista)

Type
Label
  • C-type natriuretic peptide and its relation to non-invasive indices of left ventricular function in patients with chronic heart failure (Articolo in rivista) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.peptides.2007.10.022 (literal)
Alternative label
  • Del Ry S.; Maltinti M.; Cabiati M.; Emdin M.; Giannessi D.; Morales M. A. (2008)
    C-type natriuretic peptide and its relation to non-invasive indices of left ventricular function in patients with chronic heart failure
    in Peptides (New York, NY : 1980)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Del Ry S.; Maltinti M.; Cabiati M.; Emdin M.; Giannessi D.; Morales M. A. (literal)
Pagina inizio
  • 79 (literal)
Pagina fine
  • 82 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 29 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • In: Peptides, vol. 29 pp. 79 - 82. Elsevier, 2008. (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • CNR-IFC, Pisa, IFC - Fondazione G. Monasterio Pisa (literal)
Titolo
  • C-type natriuretic peptide and its relation to non-invasive indices of left ventricular function in patients with chronic heart failure (literal)
Abstract
  • C-type natriuretic peptide (CNP) significantly increases in chronic heart failure (CHF)patients as a function of clinical severity. Aim of this study was to evaluate in CHF patients the relationship between circulating CNP concentrations and echo-Doppler conventional indices of left ventricular (LV) function as well as less load independent parameters as dP/dt. LV ejection fraction (EF), left ventricular end-diastolic dimension (LVEDD) and LV dP/dt were evaluated together with plasma CNP levels in 38 patients with CHF and in 63 controls. CNP levels resulted significantly higher in CHF patients than in controls (7.19 0.59 pg/ml vs. 2.52 0.12 pg/ml, p 0.0001). A significant correlation between dP/dt and CNP levels (r 600, n = 13): 8.46 0.69 and 4.75 0.75 pg/ml, respectively, p 0.001. This is the first study that reports a correlation between CNP and dP/ dt in CHF patients, thus suggesting a possible role on cardiac contractility. (literal)
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