Age-related changes in endothelin-1 receptor subtypes in rat heart (Articolo in rivista)

Type
Label
  • Age-related changes in endothelin-1 receptor subtypes in rat heart (Articolo in rivista) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1080/03610730802070233 (literal)
Alternative label
  • Del Ry S.; Maltinti M.; Giannessi D; Cavallini G.;Bergamini E. (2008)
    Age-related changes in endothelin-1 receptor subtypes in rat heart
    in Experimental aging research
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Del Ry S.; Maltinti M.; Giannessi D; Cavallini G.;Bergamini E. (literal)
Pagina inizio
  • 251 (literal)
Pagina fine
  • 266 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 34 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • In: Experimental Aging Research, vol. 34 (3) pp. 251 - 266. Routledge Taylor and Francis group, 2008. (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • CNR-IFC,Pisa, Universita' di Pisa (literal)
Titolo
  • Age-related changes in endothelin-1 receptor subtypes in rat heart (literal)
Abstract
  • Density, affinity, and subtype distribution of endothelin-1 (ET-1) binding sites were determined in rat cardiac tissue as a function of age in order to evaluate the association of alterations in the endothelin receptor system and aging in the heart. A significant decrease in the receptor subtype ET-A, which represents the 70-80 % of the total receptor population in cardiac tissue of 3-and 12-month-old rats, was observed in 24-month-old rats with respect to the younger groups. These findings indicate an alteration in ET-1 cardiac receptors associated with aging, mainly due to a variation in the receptor subtype distribution. (literal)
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