Presence of a functional TSH receptor on human erythrocytes (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Presence of a functional TSH receptor on human erythrocytes (Articolo in rivista) (literal)

Anno

• 2007-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.biopha.2007.04.009 (literal)

Alternative label

• Balzan S.; Nicolini G.; Forini F.; Boni G.; Del Carratore R.; Nicolini A.; Carpi A.; Iervasi G. (2007)
  Presence of a functional TSH receptor on human erythrocytes
  in Biomedicine & pharmacotherapy
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Balzan S.; Nicolini G.; Forini F.; Boni G.; Del Carratore R.; Nicolini A.; Carpi A.; Iervasi G. (literal)

Pagina inizio

• 463 (literal)

Pagina fine

• 467 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 61 (literal)

Rivista

• Biomedicine & pharmacotherapy (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• In: Biomedicine & Pharmacotherapy, vol. 61 (8) pp. 463 - 467. Elsevier, 2007. (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 8 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Institute of Clinical Physiology, CNR, Via Moruzzi 1, Pisa 56124, Italy Division of Nuclear Medicine, Department of Oncology, University of Pisa, Pisa, Italy Department of Reproduction and Ageing, University of Pisa, Pisa, Italy Department of Internal Medicine, University of Pisa, Pisa, Italy (literal)

Titolo

• Presence of a functional TSH receptor on human erythrocytes (literal)

Abstract

• The presence of thyrotropin receptors (TSHR) has been reported in some extrathyroidal tissues but its physio-pathological role still remains unclear. TSH (seems to) affects the human erythrocytes Na+/K+-ATPase in vitro, however receptors on erythrocytes have not yet been described. In this work the effect of recombinant human TSH (rhTSH) on sites number and activity of erythrocyte Na+/K+-ATPase was investigated in a group of thyroidectomized patient enrolled for rhTSH test. As detected by 3H-ouabain binding, rhTSH administration induced a significant increase in the number of sites (p = 0.005) and in the Kd (p = 0.006) of Na+/K+-ATPase. rhTSH did not induce significant difference in Na+/K+-ATPase activity measured by 86Rb uptake. 125I-TSH binding studies and Western blotting data showed the existence of TSHR in the erythrocytes of healthy donors. In conclusion The TSH action on Na+/K+-ATPase of human erythrocytes can be explained by the presence of TSHR (literal)

Prodotto di

• Tassonomia clinica molecolare - Tassonomia clinica molecolare (ME.P05.003.001) (Modulo)
• Ricerca Cardiopolmonare (ME.P01.004.001) (Modulo)
• Istituto di fisiologia clinica (IFC) (Istituto)

Autore CNR

• GIORGIO IERVASI (Unità di personale interno)
• SILVANA BALZAN (Persona)
• GIUSEPPINA NICOLINI (Persona)
• MARIA RENATA DEL CARRATORE (Persona)
• FRANCESCA FORINI (Unità di personale interno)

Insieme di parole chiave

• Keywords of "Presence of a functional TSH receptor on human erythrocytes" (Insieme di parole chiave)

Incoming links:

Prodotto

• Istituto di fisiologia clinica (IFC) (Istituto)
• Ricerca Cardiopolmonare (ME.P01.004.001) (Modulo)
• Tassonomia clinica molecolare - Tassonomia clinica molecolare (ME.P05.003.001) (Modulo)

Autore CNR di

• GIORGIO IERVASI (Unità di personale interno)
• FRANCESCA FORINI (Unità di personale interno)
• MARIA RENATA DEL CARRATORE (Persona)
• GIUSEPPINA NICOLINI (Persona)
• SILVANA BALZAN (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Biomedicine & pharmacotherapy (Rivista)

Insieme di parole chiave di

• Keywords of "Presence of a functional TSH receptor on human erythrocytes" (Insieme di parole chiave)