Pioglitazone treatment increases whole body fat but not total body water in patients with non-alcoholic steatohepatitis (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Pioglitazone treatment increases whole body fat but not total body water in patients with non-alcoholic steatohepatitis (Articolo in rivista) (literal)

Anno

• 2007-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.jhep.2007.04.013 (literal)

Alternative label

• Balas B.; Belfort R.; Harrison S. A.; Darland C.; Finch J.; Schenker S.; Gastaldelli A.; Cusi K. (2007)
  Pioglitazone treatment increases whole body fat but not total body water in patients with non-alcoholic steatohepatitis
  in Journal of hepatology (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Balas B.; Belfort R.; Harrison S. A.; Darland C.; Finch J.; Schenker S.; Gastaldelli A.; Cusi K. (literal)

Pagina inizio

• 565 (literal)

Pagina fine

• 570 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.ncbi.nlm.nih.gov/pubmed/17560678 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 47 (literal)

Rivista

• Journal of hepatology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• In: Journal of Hepatology, vol. 47 pp. 565 - 570. Journal of Hepatology, 2007. (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• CNR Institute of Clinical Physiology and San Antonio TX UTHSCSA, USA (literal)

Titolo

• Pioglitazone treatment increases whole body fat but not total body water in patients with non-alcoholic steatohepatitis (literal)

Abstract

• BACKGROUND/AIMS: Non-Alcoholic Steatohepatitis (NASH) is a chronic liver disease frequently associated with insulin resistance and type 2 diabetes mellitus (T2DM). Pioglitazone reverses the metabolic and histological abnormalities of patients with impaired glucose tolerance or T2DM and NASH, but also leads to weight gain. To understand the nature of weight gain associated with pioglitazone treatment in NASH we analyzed 35 patients who completed tests for determination of whole body fat (WBF) and total body water (TBW). METHODS: Twenty-one patients received pioglitazone and 14 placebo in a double-blind, randomized fashion for a period of 6 months. WBF and TBW were measured before and after treatment using DXA, a water dilution technique and bioimpedance. RESULTS: Pioglitazone increased body weight (from 93.6+/-4.2 to 96.1+/-4.5 kg, p0.003) and WBF measured with DXA (from 32.9+/-2.1 to 35.4+/-2.5 kg, p0.002) while no changes were seen with placebo. Total body water was not altered significantly either after pioglitazone (from 45.4+/-2.3 to 45.6+/-2.7 l, p (literal)

Prodotto di

• Tassonomia clinica molecolare - Tassonomia clinica molecolare (ME.P05.003.001) (Modulo)
• Istituto di fisiologia clinica (IFC) (Istituto)

Autore CNR

• AMALIA GASTALDELLI (Persona)

Insieme di parole chiave

• Parole chiave di "Pioglitazone treatment increases whole body fat but not total body water in patients with non-alcoholic steatohepatitis" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• AMALIA GASTALDELLI (Persona)

Prodotto

• Istituto di fisiologia clinica (IFC) (Istituto)
• Tassonomia clinica molecolare - Tassonomia clinica molecolare (ME.P05.003.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of hepatology (Rivista)

Insieme di parole chiave di

• Parole chiave di "Pioglitazone treatment increases whole body fat but not total body water in patients with non-alcoholic steatohepatitis" (Insieme di parole chiave)