Age-related oxidative stress modulation by smoking habit and obesity. (Articolo in rivista)

Type
Label
  • Age-related oxidative stress modulation by smoking habit and obesity. (Articolo in rivista) (literal)
Anno
  • 2009-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.clinbiochem.2008.11.017 (literal)
Alternative label
  • Vassalle C, Maffei S, Ndreu R, Mercuri A. (2009)
    Age-related oxidative stress modulation by smoking habit and obesity.
    in Clinical chemistry (Baltim. Md.)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Vassalle C, Maffei S, Ndreu R, Mercuri A. (literal)
Pagina inizio
  • 739 (literal)
Pagina fine
  • 741 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 42 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 7-8 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • G Monasterio Foundation and Institute of Clinical Physiology, CNR, Pisa (literal)
Titolo
  • Age-related oxidative stress modulation by smoking habit and obesity. (literal)
Abstract
  • Objective: To evaluate whether obesity and smoking habit may accelerate the age-related increase of oxidative stress. Methods: The Oxidative-INDEX, a score reflecting both oxidative and antioxidant counterparts, was estimated in 179 subjects (50 males, aged 16-79 years). Results: Oxidative stress results were elevated in obese and smoker subjects. Adjusted logistic regression analysis indicated obesity and smoking as independent variables for elevated Oxidative-INDEX (odds ratio=4.8 and 3.1, respectively). Oxidative-INDEX steadily rises at a mean rate of 5.3% (0.017 AU) per year in the overall population, showing twice and three times higher annual rate increase in smokers and obese subjects. Conclusion: Our results suggest the pro-ageing effects of cigarette smoking and obesity by a more rapid and sharp elevation of the oxidative stress status. (literal)
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